OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+20.47%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$239M
AUM Growth
+$239M
Cap. Flow
+$7.57M
Cap. Flow %
3.16%
Top 10 Hldgs %
37.89%
Holding
60
New
11
Increased
16
Reduced
16
Closed
7

Top Buys

1
RLYP
RELYPSA INC COM
RLYP
$6.24M
2
ASRT icon
Assertio
ASRT
$5.44M
3
SAGE
Sage Therapeutics
SAGE
$4.66M
4
BPMC
Blueprint Medicines
BPMC
$3.82M
5
LJPC
La Jolla Pharmaceutical Company
LJPC
$3.78M

Top Sells

1
CMRX
Chimerix, Inc.
CMRX
$11.8M
2
ZSPH
ZS PHARMA INC COMS TK (DE)
ZSPH
$6.24M
3
CEMP
Cempra, Inc.
CEMP
$4.98M
4
NBIX icon
Neurocrine Biosciences
NBIX
$3.96M
5
TNXP icon
Tonix Pharmaceuticals
TNXP
$3.02M

Sector Composition

1 Healthcare 79.19%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TGTX icon
26
TG Therapeutics
TGTX
$5.03B
$3.58M 1.5%
300,000
+40,000
+15% +$477K
INDP icon
27
Indaptus Therapeutics
INDP
$5.98M
$3.38M 1.41%
630,000
– –
AMRN
28
Amarin Corp
AMRN
$311M
$3.33M 1.39%
1,760,000
– –
NBIX icon
29
Neurocrine Biosciences
NBIX
$13.5B
$3.11M 1.3%
55,000
-70,000
-56% -$3.96M
AVDL
30
Avadel Pharmaceuticals
AVDL
$1.42B
$3.05M 1.28%
250,000
-60,000
-19% -$733K
AGRX
31
DELISTED
Agile Therapeutics, Inc
AGRX
$2.93M 1.22%
300,000
-85,000
-22% -$839K
CORI
32
DELISTED
Corium International, Inc.
CORI
$2.88M 1.21%
+355,000
New +$2.88M
TRIL
33
DELISTED
Trillium Therapeutics Inc.
TRIL
$2.65M 1.11%
210,000
-35,275
-14% -$445K
XENE icon
34
Xenon Pharmaceuticals
XENE
$2.99B
$2.41M 1.01%
300,000
+148,700
+98% +$1.2M
XOMA icon
35
Xoma
XOMA
$421M
$2.26M 0.95%
1,700,000
-1,250,000
-42% -$1.66M
ZGNX
36
DELISTED
Zogenix, Inc.
ZGNX
$2.21M 0.92%
150,000
-100,000
-40% -$1.47M
ALDR
37
DELISTED
Alder Biopharmaceuticals, Inc.
ALDR
$2.15M 0.9%
65,000
+48,900
+304% +$1.62M
NBRV
38
DELISTED
Nabriva Therapeutics plc Ordinary Shares Ireland
NBRV
$2.12M 0.88%
+220,000
New +$2.12M
CYTO
39
DELISTED
Altamira Therapeutics Ltd. Common Shares 0.01 SF (Bermuda)
CYTO
$1.83M 0.77%
375,000
+20,000
+6% +$367K
TENX icon
40
Tenax Therapeutics
TENX
$27.5M
$1.77M 0.74%
540,000
-95,000
-15% -$313K
CYNA
41
DELISTED
CYNAPSUS THERAPEUTICS INC COM PAR NO PAR (CANADA)
CYNA
$1.68M 0.7%
110,000
+81,000
+279% +$1.24M
AXDX
42
DELISTED
Accelerate Diagnostics
AXDX
$1.61M 0.67%
75,000
-20,000
-21% -$430K
CLLS
43
Cellectis
CLLS
$260M
$1.55M 0.65%
+50,000
New +$1.55M
MGNX icon
44
MacroGenics
MGNX
$121M
$1.08M 0.45%
+35,000
New +$1.08M
VTAE
45
DELISTED
VITAE PHARMACEUTICALS INC COMMON STOCK
VTAE
$1.06M 0.44%
+58,500
New +$1.06M
IMMU
46
DELISTED
Immunomedics Inc
IMMU
$890K 0.37%
+290,000
New +$890K
SGMO icon
47
Sangamo Therapeutics
SGMO
$161M
$548K 0.23%
+60,000
New +$548K
EVOK icon
48
Evoke Pharma
EVOK
$8.26M
$429K 0.18%
130,000
-130,000
-50% -$429K
BLRX
49
BioLineRX
BLRX
$15.5M
$325K 0.14%
250,000
– –
CELGZ
50
DELISTED
Celgene Corporation Contingent Value Rights
CELGZ
– –
-340,000
Closed -$547K
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