OM

Opaleye Management Portfolio holdings

AUM $494M
This Quarter Return
+29.48%
1 Year Return
+68.17%
3 Year Return
+608.37%
5 Year Return
+807.76%
10 Year Return
+24,567.28%
AUM
$215M
AUM Growth
+$215M
Cap. Flow
-$17.2M
Cap. Flow %
-8.01%
Top 10 Hldgs %
52.76%
Holding
47
New
11
Increased
10
Reduced
9
Closed
10

Top Buys

1
AMAG
AMAG Pharmaceuticals, Inc.
AMAG
$10.4M
2
MDXG icon
MiMedx Group
MDXG
$6.14M
3
ADMS
Adamas Pharmaceuticals, Inc.
ADMS
$4.46M
4
AMRN
Amarin Corp
AMRN
$4.1M
5
NBIX icon
Neurocrine Biosciences
NBIX
$3.97M

Top Sells

1
PCYC
PHARMACYCLICS INC
PCYC
$10.4M
2
TVTX icon
Travere Therapeutics
TVTX
$10.1M
3
CMRX
Chimerix, Inc.
CMRX
$9.05M
4
ARAV
Aravive, Inc. Common Stock
ARAV
$5.28M
5
GNMK
GenMark Diagnostics, Inc
GNMK
$4.56M

Sector Composition

1 Healthcare 83.51%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TVRD
26
Tvardi Therapeutics, Inc. Common Stock
TVRD
$270M
$3.17M 1.47%
315,000
+235,000
+294% +$2.36M
ZSPH
27
DELISTED
ZS PHARMA INC COMS TK (DE)
ZSPH
$3.16M 1.47%
+75,000
New +$3.16M
IOVA icon
28
Iovance Biotherapeutics
IOVA
$800M
$2.42M 1.12%
+200,000
New +$2.42M
AXDX
29
DELISTED
Accelerate Diagnostics
AXDX
$2.26M 1.05%
100,600
+600
+0.6% +$13.5K
TENX icon
30
Tenax Therapeutics
TENX
$27.5M
$1.98M 0.92%
606,200
+166,200
+38% +$520K
EVOK icon
31
Evoke Pharma
EVOK
$8.26M
$1.73M 0.8%
245,000
+5,000
+2% +$34.5K
MGNX icon
32
MacroGenics
MGNX
$121M
$1.57M 0.73%
+50,000
New +$1.57M
BDSI
33
DELISTED
BioDelivery Sciences International, Inc.
BDSI
$1.48M 0.68%
+140,500
New +$1.48M
CELGZ
34
DELISTED
Celgene Corporation Contingent Value Rights
CELGZ
$1.46M 0.68%
490,000
-85,000
-15% -$252K
BLRX
35
BioLineRX
BLRX
$15.5M
$528K 0.25%
250,000
– –
NSPR icon
36
InspireMD
NSPR
$101M
$400K 0.19%
1,250,000
+1,250,000
– –
TCON
37
DELISTED
TRACON Pharmaceuticals, Inc. Common Stock
TCON
$171K 0.08%
+12,172
New +$171K
PCYC
38
DELISTED
PHARMACYCLICS INC
PCYC
– –
-85,000
Closed -$10.4M
HZNP
39
DELISTED
Horizon Therapeutics Public Limited Company Ordinary Shares
HZNP
– –
-220,000
Closed -$2.84M
GNMK
40
DELISTED
GenMark Diagnostics, Inc
GNMK
– –
-335,000
Closed -$4.56M
CSII
41
DELISTED
Cardiovascular Systems, Inc.
CSII
– –
-125,000
Closed -$3.76M
PRTK
42
DELISTED
Paratek Pharmaceuticals, Inc.
PRTK
– –
-80,000
Closed -$3.08M
ARAV
43
DELISTED
Aravive, Inc. Common Stock
ARAV
– –
-235,000
Closed -$5.28M
LAB icon
44
Standard BioTools
LAB
$493M
– –
-95,000
Closed -$3.2M
CPRX icon
45
Catalyst Pharmaceutical
CPRX
$2.42B
– –
-975,000
Closed -$2.9M
ALNY icon
46
Alnylam Pharmaceuticals
ALNY
$58.6B
– –
-29,100
Closed -$2.82M
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