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OFM

Omega Fund Management Portfolio holdings

AUM $186M
1-Year Est. Return 155.23%
This Fund
S&P 500
This Quarter Est. Return
+6.68%
1 Year Est. Return
+155.23%
3 Year Est. Return
+106.31%
5 Year Est. Return
+162.6%
10 Year Est. Return
+764.79%
AUM
$154M
AUM Growth
-$15M
Cap. Flow
-$7.5M
Cap. Flow %
-4.86%
Top 10 Hldgs %
97.77%
Holding
13
New
–
Increased
–
Reduced
2
Closed
–

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
NUVB icon
Nuvation Bio
NUVB
+$4.23M
2
KMTS
Kestra Medical Technologies
KMTS
+$3.27M

Sector Composition

Rank Sector Weight
1 Healthcare 99.82%
2 Miscellaneous 0.18%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BBNX
1
Beta Bionics
BBNX
$784M
$28.9M 18.75%
1,988,287
– –
KMTS
2
Kestra Medical Technologies
KMTS
$1.41B
$27.3M 17.67%
1,645,893
-150,000
-8% -$3.27M
UPB
3
Upstream Bio Inc
UPB
$326M
$22.4M 14.48%
2,036,293
– –
NUVB icon
4
Nuvation Bio
NUVB
$2.29B
$21.5M 13.94%
11,042,728
-2,029,612
-16% -$4.23M
BCAX
5
Bicara Therapeutics
BCAX
$1.56B
$20.5M 13.26%
2,204,650
– –
REPL icon
6
Replimune Group
REPL
$1.36B
$18.3M 11.88%
1,975,203
– –
LXEO icon
7
Lexeo Therapeutics
LXEO
$368M
$4.76M 3.08%
1,184,636
– –
IMA
8
ImageneBio Inc
IMA
$56.9M
$3.01M 1.95%
187,427
– –
SANA icon
9
Sana Biotechnology
SANA
$949M
$2.3M 1.49%
843,750
– –
ALMS
10
Alumis Inc
ALMS
$1.27B
$1.96M 1.27%
653,223
– –
ENGN icon
11
enGene Therapeutics
ENGN
$124M
$1.92M 1.24%
526,357
– –
IMUX icon
12
Immunic
IMUX
$166M
$1.25M 0.81%
178,816
– –
ENGNW icon
13
enGene Therapeutics Warrants
ENGNW
$273K 0.18%
321,502
– –

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FWM
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Omega Fund Management's Q2 2025 Portfolio in Review

As of Q2 2025, Omega Fund Management held 13 positions worth $154M, down 8.9% from $169M the previous quarter. Its ten largest holdings account for 98% of the portfolio.

Omega Fund Management withdrew a net $7.5M in Q2 2025, reducing 2 holdings. Its largest reduction was Nuvation Bio, cutting an estimated $4.23M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier, followed by Miscellaneous.

  • Omega Fund Management's biggest Q2 2025 reduction was Nuvation Bio, cutting an estimated $4.23M.
  • Omega Fund Management's ten largest holdings make up 98% of its $154M portfolio in Q2 2025.
  • Omega Fund Management opened 0 new positions and closed 0 in Q2 2025.
  • Omega Fund Management's portfolio value fell 8.9% quarter-over-quarter to $154M.

Based on Omega Fund Management's 13F filing for Q2 2025, filed 14 Aug 2025.