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Omega Fund Management Portfolio holdings

AUM $163M
1-Year Est. Return 107.06%
This Fund
S&P 500
This Quarter Est. Return
-17.32%
1 Year Est. Return
+107.06%
3 Year Est. Return
+111.75%
5 Year Est. Return
+84.24%
10 Year Est. Return
+495.59%
AUM
$163M
AUM Growth
-$123M
Cap. Flow
-$51.4M
Cap. Flow %
-31.48%
Top 10 Hldgs %
100%
Holding
11
New
–
Increased
1
Reduced
2
Closed
1

Top Buys

Rank Stock Value
1
BCAX
Bicara Therapeutics
BCAX
+$3.23M

Top Sells

Rank Stock Value
1
UPB
Upstream Bio Inc
UPB
+$36M
2
ALMS
Alumis Inc
ALMS
+$10.3M
3
KMTS
Kestra Medical Technologies
KMTS
+$8.28M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BCAX
1
Bicara Therapeutics
BCAX
$1.78B
$47.6M 29.16%
2,392,150
+187,500
+9% +$3.23M
NUVB icon
2
Nuvation Bio
NUVB
$2.24B
$34.7M 21.25%
8,081,089
– –
BBOT
3
BridgeBio Oncology
BBOT
$707M
$29.4M 18.05%
3,289,661
– –
KMTS
4
Kestra Medical Technologies
KMTS
$1.23B
$20.4M 12.49%
1,022,149
-351,442
-26% -$8.28M
BBNX
5
Beta Bionics
BBNX
$706M
$13.2M 8.08%
1,316,183
– –
ENGN icon
6
enGene Therapeutics
ENGN
$122M
$5.97M 3.66%
876,357
– –
ALMS
7
Alumis Inc
ALMS
$3.57B
$5.31M 3.26%
241,255
-411,968
-63% -$10.3M
SANA icon
8
Sana Biotechnology
SANA
$885M
$2.43M 1.49%
843,750
– –
IMA
9
ImageneBio Inc
IMA
$63.1M
$2.28M 1.4%
455,361
– –
REPL icon
10
Replimune Group
REPL
$814M
$1.91M 1.17%
248,672
– –
UPB
11
Upstream Bio Inc
UPB
$349M
– –
-1,326,293
Closed -$36M

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HCCM
Hudson Canyon Capital Management New York $163M AUM 33.71% 1-Year Est. Return
PBO
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PCR
Potrero Capital Research San Francisco, California $163M AUM 79.07% 1-Year Est. Return
BCM
Basso Capital Management Stamford, Connecticut $163M AUM 21.95% 1-Year Est. Return
IVGAI
Index Venture Growth Associates IV St. Helier, Jersey $163M AUM 54.88% 1-Year Est. Return
CC
Cannell Capital Alta, Wyoming $163M AUM 40.62% 1-Year Est. Return
TCGDR
TB Capital Gestao de Recursos Rio De Janeiro $163M AUM 20.86% 1-Year Est. Return
IPWA
International Private Wealth Advisors San Diego, California $163M AUM 16.99% 1-Year Est. Return

Omega Fund Management's Q1 2026 Portfolio in Review

As of Q1 2026, Omega Fund Management held 11 positions worth $163M, down 43% from $287M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Omega Fund Management withdrew a net $51.4M in Q1 2026, closing 1 position and reducing 2 holdings. Its most notable exit was Upstream Bio Inc, an estimated $36M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

Against the trend, Omega Fund Management added an estimated $3.23M to Bicara Therapeutics.

  • Omega Fund Management added most to Bicara Therapeutics in Q1 2026, an estimated $3.23M increase.
  • Omega Fund Management's biggest Q1 2026 reduction was Alumis Inc, cutting an estimated $10.3M.
  • Omega Fund Management fully exited Upstream Bio Inc in Q1 2026, selling an estimated $36M.
  • Omega Fund Management's ten largest holdings make up 100% of its $163M portfolio in Q1 2026.
  • Omega Fund Management opened 0 new positions and closed 1 in Q1 2026.
  • Omega Fund Management's portfolio value fell 43% quarter-over-quarter to $163M.

Based on Omega Fund Management's 13F filing for Q1 2026, filed 15 May 2026.