Manulife (Manufacturers Life Insurance)
SION

Manulife (Manufacturers Life Insurance)’s Sionna Therapeutics SION Stock Holding History

Manulife (Manufacturers Life Insurance)’s Portfolio SION Stock Details SION Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$2.58M Sell
64,458
-4,966
-7% -$190K ﹤0.01% 1399
2025
Q4 		$2.87M Buy
69,424
+37,344
+116% +$1.42M ﹤0.01% 1385
2025
Q3 		$943K Sell
32,080
-5,958
-16% -$130K ﹤0.01% 1881
2025
Q2 		$660K Buy
38,038
+4,489
+13% +$58.8K ﹤0.01% 2033
2025
Q1 		$351K Buy
+33,549
New +$548K ﹤0.01% 2289

Other funds holding SION

RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
TGA
TPG GP A Fort Worth, Texas $3.68B AUM 14.99% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
Viking Global Investors
Viking Global Investors Stamford, Connecticut $35.7B AUM 21.3% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
Jennison Associates
Jennison Associates New York $167B AUM 44.17% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

Manulife (Manufacturers Life Insurance)'s SION Position: Q1 2026 in Review

Manulife (Manufacturers Life Insurance) reduced its Sionna Therapeutics (SION) stake by 7.2% in Q1 2026, selling an estimated $190K and leaving 64,458 shares worth $2.58M. The position accounts for ﹤0.01% of the portfolio, ranked #1399.

Manulife (Manufacturers Life Insurance) first reported a position in SION in Q1 2025 and has held it in 5 quarters since. The position peaked at $2.87M in Q4 2025. 122 funds tracked by Wall St. Rank hold SION as of Q1 2026.

  • Manulife (Manufacturers Life Insurance) held 64,458 shares of Sionna Therapeutics worth $2.58M as of Q1 2026.
  • Manulife (Manufacturers Life Insurance) sold 4,966 Sionna Therapeutics shares in Q1 2026, an estimated $190K.
  • Sionna Therapeutics made up ﹤0.01% of Manulife (Manufacturers Life Insurance)'s portfolio in Q1 2026, its #1399 holding.
  • Manulife (Manufacturers Life Insurance) first reported a position in Sionna Therapeutics in Q1 2025 and has held it in 5 quarters since.
  • Manulife (Manufacturers Life Insurance)'s Sionna Therapeutics position peaked at $2.87M in Q4 2025.
  • 122 funds tracked by Wall St. Rank held Sionna Therapeutics as of Q1 2026.

Based on Manulife (Manufacturers Life Insurance)'s 13F filing for Q1 2026, filed 15 May 2026.