Manulife (Manufacturers Life Insurance)
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Manulife (Manufacturers Life Insurance)’s Lyell Immunopharma LYEL Stock Holding History

Manulife (Manufacturers Life Insurance)’s Portfolio LYEL Stock Details LYEL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-24,419
Closed -$216K – 2964
2025
Q2 		$216K Sell
24,419
-1,272
-5% -$11.6K ﹤0.01% 2519
2025
Q1 		$276K Sell
25,691
-1,902
-7% -$23.3K ﹤0.01% 2371
2024
Q4 		$353K Sell
27,593
-35
-0.1% -$694 ﹤0.01% 2386
2024
Q3 		$763K Sell
27,628
-30
-0.1% -$882 ﹤0.01% 2057
2024
Q2 		$802K Buy
27,658
+3,485
+14% +$166K ﹤0.01% 1965
2024
Q1 		$1.08M Buy
24,173
+957
+4% +$41K ﹤0.01% 1826
2023
Q4 		$901K Hold
23,216
– – ﹤0.01% 1852
2023
Q3 		$683K Buy
23,216
+22
+0.1% +$1.04K ﹤0.01% 1972
2023
Q2 		$1.48M Buy
23,194
+11,244
+94% +$622K ﹤0.01% 1501
2023
Q1 		$564K Buy
11,950
+972
+9% +$52K ﹤0.01% 1936
2022
Q4 		$735K Buy
10,978
+53
+0.5% +$5.26K ﹤0.01% 1761
2022
Q3 		$1.61M Sell
10,925
-63
-0.6% -$8.53K ﹤0.01% 1436
2022
Q2 		$1.46M Buy
10,988
+1,847
+20% +$189K ﹤0.01% 1498
2022
Q1 		$961K Buy
9,141
+8,250
+926% +$1,000K ﹤0.01% 1777
2021
Q4 		$135 Buy
891
+140
+19% +$31.2K ﹤0.01% 3004
2021
Q3 		$222K Buy
+751
New +$225K ﹤0.01% 2909

Other funds holding LYEL

AVM
Arch Venture Management Chicago, Illinois $677M AUM 322.07% 1-Year Est. Return
MM
MWG Management Road Town, Tortola, British Virgin Islands $81.3M AUM 2.28% 1-Year Est. Return
FCMI
Foresite Capital Management IV Larkspur, California $237M AUM 107.53% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
OPL
Orland Properties Ltd Road Town, Tortola, British Virgin Islands $202M AUM 2.79% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
AC
Almitas Capital Santa Monica, California $443M AUM 42.36% 1-Year Est. Return
FCMV
Foresite Capital Management V Larkspur, California $271M AUM 309.87% 1-Year Est. Return
VP
venBio Partners San Francisco, California $281M AUM 261.03% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

Manulife (Manufacturers Life Insurance)'s LYEL Position: Q3 2025 in Review

Manulife (Manufacturers Life Insurance) sold out of Lyell Immunopharma (LYEL) in Q3 2025, closing a stake of 24,419 shares — an estimated $216K sold.

Manulife (Manufacturers Life Insurance) first reported a position in LYEL in Q3 2021 and held it in 16 quarters. The position peaked at $1.61M in Q3 2022. 59 funds tracked by Wall St. Rank hold LYEL as of Q3 2025.

  • Manulife (Manufacturers Life Insurance) reported no remaining Lyell Immunopharma position as of Q3 2025 after selling out during the quarter.
  • Manulife (Manufacturers Life Insurance) sold 24,419 Lyell Immunopharma shares in Q3 2025, an estimated $216K.
  • Manulife (Manufacturers Life Insurance) first reported a position in Lyell Immunopharma in Q3 2021 and held it in 16 quarters.
  • Manulife (Manufacturers Life Insurance)'s Lyell Immunopharma position peaked at $1.61M in Q3 2022.
  • 59 funds tracked by Wall St. Rank held Lyell Immunopharma as of Q3 2025.

Based on Manulife (Manufacturers Life Insurance)'s 13F filing for Q3 2025, filed 14 Nov 2025.