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MSR
Main Street Research Portfolio holdings
AUM
$2.12B
1-Year Est. Return
67.44%
This Fund
S&P 500
This Quarter
Est. Return
+4.75%
1 Year Est. Return
+67.44%
3 Year Est. Return
+232.37%
5 Year Est. Return
+381.46%
10 Year Est. Return
+1,630.85%
AUM
$1.75B
AUM Growth
-$103M
(-5.5%)
Cap. Flow
-$128M
Cap. Flow
% of AUM
-7.35%
Top 10 Holdings %
Top 10 Hldgs %
45.32%
Holding
146
New
17
Increased
25
Reduced
77
Closed
17
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P Biotech ETF
XBI
|
+$41.3M |
| 2 |
Johnson & Johnson
JNJ
|
+$33.2M |
| 3 |
AstraZeneca
AZN
|
+$32.6M |
| 4 |
iShares MSCI South Korea ETF
EWY
|
+$32.5M |
| 5 |
Caterpillar
CAT
|
+$31.4M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Netflix
NFLX
|
+$45.1M |
| 2 |
T-Mobile US
TMUS
|
+$37.8M |
| 3 |
Mercado Libre
MELI
|
+$37M |
| 4 |
Spotify
SPOT
|
+$35.2M |
| 5 |
Trane Technologies
TT
|
+$32.1M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 35.88% |
| 2 | Financials | 16.32% |
| 3 | Communication Services | 9.11% |
| 4 | Healthcare | 7.73% |
| 5 | Consumer Staples | 6.59% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
126
Gilead Sciences
GILD
$162B
| $224K | 0.01% |
+1,829
| New | +$222K |
|
127
NextEra Energy
NEE
$176B
| $224K | 0.01% |
+2,795
| New | +$232K |
|
128
Brookfield
BN
$108B
| $212K | 0.01% |
+4,628
| New | +$211K |
|
129
Hims & Hers Health
HIMS
$6.87B
| $201K | 0.01% |
6,200
| – | – |
|
130
Arista Networks
ANET
$243B
| – | – |
-34,884
| Closed | -$5.08M |
|
131
Apollo Global Management
APO
$73.7B
| – | – |
-217,067
| Closed | -$28.9M |
|
132
CrowdStrike
CRWD
$211B
| – | – |
-3,192
| Closed | -$391K |
|
133
Datadog
DDOG
$81.6B
| – | – |
-1,416
| Closed | -$202K |
|
134
DraftKings
DKNG
$11B
| – | – |
-6,500
| Closed | -$243K |
|
135
Fortinet
FTNT
$117B
| – | – |
-4,190
| Closed | -$352K |
|
136
Idexx Laboratories
IDXX
$46.5B
| – | – |
-411
| Closed | -$263K |
|
137
Gartner
IT
$11.7B
| – | – |
-2,153
| Closed | -$566K |
|
138
Coca-Cola
KO
$374B
| – | – |
-3,597
| Closed | -$239K |
|
139
Cheniere Energy
LNG
$54.9B
| – | – |
-1,008
| Closed | -$237K |
|
|
140
Mercado Libre
MELI
$92.8B
| – | – |
-15,833
| Closed | -$37M |
|
141
Pacific Biosciences
PACB
$363M
| – | – |
-142,100
| Closed | -$182K |
|
142
PayPal
PYPL
$51.1B
| – | – |
-3,854
| Closed | -$258K |
|
|
143
Spotify
SPOT
$97.7B
| – | – |
-50,422
| Closed | -$35.2M |
|
144
Sysco
SYY
$40.4B
| – | – |
-2,475
| Closed | -$204K |
|
145
Teledyne Technologies
TDY
$31.9B
| – | – |
-362
| Closed | -$212K |
|
146
TMC The Metals Company
TMC
$1.78B
| – | – |
-10,000
| Closed | -$63.7K |
|
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Main Street Research's Q4 2025 Portfolio in Review
As of Q4 2025, Main Street Research held 146 positions worth $1.75B, down 5.5% from $1.85B the previous quarter. Its ten largest holdings account for 45% of the portfolio.
Main Street Research withdrew a net $128M in Q4 2025, closing 17 positions and reducing 77 holdings. Its most notable exit was Mercado Libre, an estimated $37M position sold in full.
By sector, the portfolio is most concentrated in Technology at 36% of assets, up from 36% a quarter earlier, followed by Financials and Communication Services.
Against the trend, Main Street Research opened a new position in State Street SPDR S&P Biotech ETF worth $44M.
- Main Street Research's largest Q4 2025 buy was State Street SPDR S&P Biotech ETF: 360,526 shares worth $44M.
- Main Street Research added most to Johnson & Johnson in Q4 2025, an estimated $33.2M increase.
- Main Street Research's biggest Q4 2025 reduction was Netflix, cutting an estimated $45.1M.
- Main Street Research fully exited Mercado Libre in Q4 2025, selling an estimated $37M.
- Main Street Research's ten largest holdings make up 45% of its $1.75B portfolio in Q4 2025.
- Main Street Research opened 17 new positions and closed 17 in Q4 2025.
- Main Street Research's portfolio value fell 5.5% quarter-over-quarter to $1.75B.
Based on Main Street Research's 13F filing for Q4 2025, filed 9 Feb 2026.