Jane Street
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Jane Street’s PDS Biotechnology PDSB Stock Holding History

Jane Street’s Portfolio PDSB Stock Details PDSB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-36,581
Closed -$36.9K – 12060
2025
Q3 		$36.9K Sell
36,581
-32,670
-47% -$38.4K ﹤0.01% 10418
2025
Q2 		$92.1K Buy
+69,251
New +$94K ﹤0.01% 8987
2025
Q1 		– Sell
-35,644
Closed -$58.1K – 10319
2024
Q4 		$58.1K Buy
+35,644
New +$94.3K ﹤0.01% 8930
2024
Q3 		– Sell
-114,032
Closed -$334K – 10193
2024
Q2 		$334K Buy
114,032
+38,753
+51% +$124K ﹤0.01% 7639
2024
Q1 		$298K Buy
75,279
+54,917
+270% +$283K ﹤0.01% 7578
2023
Q4 		$101K Buy
+20,362
New +$101K ﹤0.01% 8573
2023
Q3 		– Sell
-39,422
Closed -$198K – 9183
2023
Q2 		$198K Sell
39,422
-84,514
-68% -$553K ﹤0.01% 7682
2023
Q1 		$762K Buy
123,936
+92,807
+298% +$759K ﹤0.01% 5545
2022
Q4 		$411K Buy
31,129
+7,967
+34% +$56.2K ﹤0.01% 6478
2022
Q3 		$69K Buy
+23,162
New +$98.3K ﹤0.01% 8807
2022
Q1 		– Sell
-19,329
Closed -$157K – 10854
2021
Q4 		$157K Buy
19,329
+2,590
+15% +$27.9K ﹤0.01% 8975
2021
Q3 		$249K Buy
+16,739
New +$209K ﹤0.01% 8517
2018
Q4 		– Sell
-1,024
Closed -$17K – 5503
2018
Q3 		$17K Sell
1,024
-2,033
-67% -$36.5K ﹤0.01% 4977
2018
Q2 		$63K Buy
+3,057
New +$63.8K ﹤0.01% 4795

Other funds holding PDSB

AC
Armistice Capital New York $5.62B AUM 36.06% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
William Blair & Company
William Blair & Company Chicago, Illinois $34.9B AUM 18.88% 1-Year Est. Return
Commonwealth Equity Services
Commonwealth Equity Services Waltham, Massachusetts $71.6B AUM 21.08% 1-Year Est. Return
Squarepoint
Squarepoint New York $85.1B AUM 20.93% 1-Year Est. Return
IWA
Inspirion Wealth Advisors Libertyville, Illinois $874M AUM 16.23% 1-Year Est. Return
Renaissance Technologies
Renaissance Technologies New York $63.9B AUM 45.56% 1-Year Est. Return

Jane Street's PDSB Position: Q4 2025 in Review

Jane Street sold out of PDS Biotechnology (PDSB) in Q4 2025, closing a stake of 36,581 shares — an estimated $36.9K sold.

Jane Street first reported a position in PDSB in Q2 2018 and held it in 14 quarters. The position peaked at $762K in Q1 2023. 44 funds tracked by Wall St. Rank hold PDSB as of Q4 2025.

  • Jane Street reported no remaining PDS Biotechnology position as of Q4 2025 after selling out during the quarter.
  • Jane Street sold 36,581 PDS Biotechnology shares in Q4 2025, an estimated $36.9K.
  • Jane Street first reported a position in PDS Biotechnology in Q2 2018 and held it in 14 quarters.
  • Jane Street's PDS Biotechnology position peaked at $762K in Q1 2023.
  • 44 funds tracked by Wall St. Rank held PDS Biotechnology as of Q4 2025.

Based on Jane Street's 13F filing for Q4 2025, filed 12 Feb 2026.