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PDS Biotechnology

44 hedge funds and large institutions have $6.07M invested in PDS Biotechnology in 2025 Q4 according to their latest regulatory filings, with 10 funds opening new positions, 11 increasing their positions, 13 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

4.14% more ownership

Funds ownership: 11.95%16.09% (+4.1%)

9% less first-time investments, than exits

New positions opened: 10 | Existing positions closed: 11

6% less funds holding

Funds holding: 4744 (-3)

9% less capital invested

Capital invested by funds: $6.64M → $6.07M (-$572K)

15% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 13

Holders
44
Holders Change
-3
Holders Change %
-6.38%
% of All Funds
0.54%
Holding in Top 10
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
New
10
Increased
11
Reduced
13
Closed
11
Calls
Puts
Net Calls
Net Calls Change
Name Holding Trade Value Shares
Change
Change in
Stake
AC
1
Armistice Capital
New York
$2.18M +$2.56M +2,834,506 New
Vanguard Group
2
Vanguard Group
Pennsylvania
$1.5M +$44.7K +49,505 +3%
BlackRock
3
BlackRock
New York
$402K +$4.23K +4,692 +0.9%
Geode Capital Management
4
Geode Capital Management
Massachusetts
$401K +$34.6K +38,399 +8%
UBS Group
5
UBS Group
Switzerland
$194K +$46.4K +51,469 +26%
William Blair & Company
6
William Blair & Company
Illinois
$192K
Commonwealth Equity Services
7
Commonwealth Equity Services
Massachusetts
$151K +$95.9K +106,300 +117%
Squarepoint
8
Squarepoint
New York
$148K -$89.4K -99,071 -34%
IWA
9
Inspirion Wealth Advisors
Illinois
$139K -$148K -163,899 -48%
Renaissance Technologies
10
Renaissance Technologies
New York
$136K -$89.4K -99,161 -36%
Northern Trust
11
Northern Trust
Illinois
$111K +$27.4K +30,401 +27%
State Street
12
State Street
Massachusetts
$103K
IGGA
13
Iron Gate Global Advisors
Utah
$57.7K
Bank of New York Mellon
14
Bank of New York Mellon
New York
$53.4K +$36.1K +40,018 +137%
TWP
15
Tempus Wealth Planning
California
$47.6K +$12.6K +14,000 +29%
Susquehanna International Group
16
Susquehanna International Group
Pennsylvania
$29.7K -$50.3K -55,778 -59%
XT
17
XTX Topco
Cayman Islands
$26.3K +$13.1K +14,519 +74%
VF
18
Virtu Financial
New York
$25K +$29K +32,099 New
ACM
19
ACT Capital Management
Pennsylvania
$23.1K +$27.1K +30,000 New
Rockefeller Capital Management
20
Rockefeller Capital Management
New York
$19.8K -$7.94K -8,803 -26%
Simplex Trading
21
Simplex Trading
Illinois
$14.7K +$6.04K +6,701 +54%
SG
22
StoneX Group
New York
$12.3K +$14.4K +16,000 New
First Manhattan
23
First Manhattan
New York
$11.5K
FDCDDQ
24
Federation des caisses Desjardins du Quebec
Quebec, Canada
$11.4K -$3.61K -4,000 -21%
GSC
25
Ground Swell Capital
South Carolina
$11.3K +$13.3K +14,703 New

PDSB Hedge Fund Activity: Q4 2025 in Review

44 of the 8,223 institutional investors tracked by Wall St. Rank reported a position in PDS Biotechnology (PDSB) for Q4 2025, worth a combined $6.07M — down 8.6% from $6.64M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of PDSB and 10 opened new positions — a net loss of 1 holder — while 13 trimmed existing stakes and 11 added.

The largest buyer was Armistice Capital, opening a new position worth an estimated $2.56M. The largest seller was Citadel Advisors, exiting entirely with an estimated $390K sold.

  • 44 institutional investors held PDS Biotechnology (PDSB) as of Q4 2025, down from 47 in Q3 2025.
  • Funds reported $6.07M of PDS Biotechnology stock for Q4 2025, down 8.6% quarter-over-quarter.
  • 10 funds opened new PDS Biotechnology positions in Q4 2025 and 11 closed out, a net change of -1 holder.
  • The largest PDS Biotechnology buyer in Q4 2025 was Armistice Capital, an estimated $2.56M added.
  • The largest PDS Biotechnology seller in Q4 2025 was Citadel Advisors, an estimated $390K sold.

Based on aggregated 13F filings for Q4 2025.