Jane Street
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Jane Street’s Opko Health OPK Stock Holding History

Jane Street’s Portfolio OPK Stock Details OPK Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q1 		– Sell
-190,800
Closed -$280K – 10283
2024
Q4 		$280K Sell
190,800
-88,500
-32% -$135K ﹤0.01% 7847
2024
Q3 		$416K Buy
279,300
+1,100
+0.4% +$1.63K ﹤0.01% 7502
2024
Q2 		$348K Buy
278,200
+174,200
+168% +$226K ﹤0.01% 7563
2024
Q1 		$125K Buy
+104,000
New +$104K ﹤0.01% 8442
2022
Q4 		– Sell
-411,800
Closed -$778K – 9844
2022
Q3 		$778K Sell
411,800
-108,900
-21% -$257K ﹤0.01% 5881
2022
Q2 		$1.32M Sell
520,700
-13,700
-3% -$39.9K ﹤0.01% 4966
2022
Q1 		$1.84M Sell
534,400
-145,100
-21% -$512K ﹤0.01% 4911
2021
Q4 		$3.27M Buy
679,500
+553,800
+441% +$2.24M ﹤0.01% 3553
2021
Q3 		$459K Sell
125,700
-14,000
-10% -$52.1K ﹤0.01% 7449
2021
Q2 		$566K Buy
139,700
+50,400
+56% +$198K ﹤0.01% 7010
2021
Q1 		$383K Sell
89,300
-110,300
-55% -$527K ﹤0.01% 7291
2020
Q4 		$788K Sell
199,600
-1,900
-0.9% -$7.93K ﹤0.01% 5050
2020
Q3 		$744K Buy
201,500
+147,800
+275% +$624K ﹤0.01% 4565
2020
Q2 		$183K Buy
+53,700
New +$120K ﹤0.01% 6424
2017
Q1 		– Sell
-21,500
Closed -$200K – 4529
2016
Q4 		$200K Buy
+21,500
New +$222K ﹤0.01% 3735
2016
Q2 		– Sell
-74,100
Closed -$770K – 4439
2016
Q1 		$770K Buy
74,100
+55,700
+303% +$509K ﹤0.01% 2113
2015
Q4 		$185K Buy
18,400
+7,800
+74% +$78.2K ﹤0.01% 3643
2015
Q3 		$89K Sell
10,600
-21,300
-67% -$282K ﹤0.01% 3382
2015
Q2 		$513K Buy
+31,900
New +$496K ﹤0.01% 2269

Other funds holding OPK

RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
WCM
Whitefort Capital Management New York $339M AUM 52.48% 1-Year Est. Return
Northern Trust
Northern Trust Chicago, Illinois $757B AUM 28.64% 1-Year Est. Return

Jane Street's OPK Position: Q1 2026 in Review

Jane Street reduced its Opko Health (OPK) stake by 37% in Q1 2026, selling an estimated $814K and leaving 1,114,375 shares worth $1.27M. The position accounts for ﹤0.01% of the portfolio, ranked #5992.

Jane Street first reported a position in OPK in Q3 2013 and has held it in 50 quarters since. The position peaked at $8.63M in Q2 2015. 235 funds tracked by Wall St. Rank hold OPK as of Q1 2026.

  • Jane Street held 1,114,375 shares of Opko Health worth $1.27M as of Q1 2026.
  • Jane Street sold 660,961 Opko Health shares in Q1 2026, an estimated $814K.
  • Opko Health made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #5992 holding.
  • Jane Street first reported a position in Opko Health in Q3 2013 and has held it in 50 quarters since.
  • Jane Street's Opko Health position peaked at $8.63M in Q2 2015.
  • 235 funds tracked by Wall St. Rank held Opko Health as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.