Jane Street
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Jane Street’s Agios Pharmaceuticals AGIO Stock Holding History

Jane Street’s Portfolio AGIO Stock Details AGIO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$7.97M Buy
214,900
+107,800
+101% +$3.27M ﹤0.01% 3105
2026
Q1 		$3.62M Sell
107,100
-44,400
-29% -$1.26M ﹤0.01% 4014
2025
Q4 		$4.12M Buy
151,500
+141,500
+1,415% +$4.96M ﹤0.01% 3530
2025
Q3 		$401K Buy
+10,000
New +$376K ﹤0.01% 8310
2024
Q2 		– Sell
-70,500
Closed -$2.06M – 9255
2024
Q1 		$2.06M Buy
70,500
+24,400
+53% +$653K ﹤0.01% 4068
2023
Q4 		$1.03M Sell
46,100
-4,600
-9% -$103K ﹤0.01% 5516
2023
Q3 		$1.25M Buy
50,700
+22,800
+82% +$603K ﹤0.01% 4824
2023
Q2 		$790K Sell
27,900
-6,300
-18% -$157K ﹤0.01% 5603
2023
Q1 		$786K Sell
34,200
-81,200
-70% -$2.16M ﹤0.01% 5476
2022
Q4 		$3.24M Sell
115,400
-45,300
-28% -$1.28M ﹤0.01% 3102
2022
Q3 		$4.54M Buy
160,700
+75,700
+89% +$2.03M ﹤0.01% 2770
2022
Q2 		$1.88M Buy
85,000
+63,000
+286% +$1.42M ﹤0.01% 4279
2022
Q1 		$640K Sell
22,000
-62,100
-74% -$1.9M ﹤0.01% 7013
2021
Q4 		$2.76M Sell
84,100
-4,900
-6% -$197K ﹤0.01% 3833
2021
Q3 		$4.11M Sell
89,000
-46,000
-34% -$2.22M ﹤0.01% 3065
2021
Q2 		$7.44M Buy
135,000
+65,300
+94% +$3.65M ﹤0.01% 2071
2021
Q1 		$3.6M Sell
69,700
-75,700
-52% -$3.75M ﹤0.01% 2916
2020
Q4 		$6.3M Buy
145,400
+99,700
+218% +$3.94M ﹤0.01% 1852
2020
Q3 		$1.6M Buy
45,700
+34,100
+294% +$1.49M ﹤0.01% 3368
2020
Q2 		$620K Buy
11,600
+4,700
+68% +$218K ﹤0.01% 4742
2020
Q1 		$245K Buy
+6,900
New +$319K ﹤0.01% 4437

Other funds holding AGIO

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $21.7B AUM 79.24% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
LCM
Lynx1 Capital Management San Juan, Puerto Rico $866M AUM 231.68% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $210B AUM 57.28% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
AC
Armistice Capital New York $8.17B AUM 68.82% 1-Year Est. Return
EAM
Erste Asset Management Vienna, Austria $12.9B AUM 52.69% 1-Year Est. Return
NAMI
Nomura Asset Management International Philadelphia, Pennsylvania $66.6B AUM

Jane Street's AGIO Position: Q2 2026 in Review

Jane Street reduced its Agios Pharmaceuticals (AGIO) stake by 28% in Q2 2026, selling an estimated $5.84M and leaving 492,598 shares worth $18.3M. The position accounts for ﹤0.01% of the portfolio, ranked #2231.

Jane Street first reported a position in AGIO in Q3 2013 and has held it in 35 quarters since. The position peaked at $30.5M in Q4 2025. 238 funds tracked by Wall St. Rank hold AGIO as of Q2 2026.

  • Jane Street held 492,598 shares of Agios Pharmaceuticals worth $18.3M as of Q2 2026.
  • Jane Street sold 192,642 Agios Pharmaceuticals shares in Q2 2026, an estimated $5.84M.
  • Agios Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #2231 holding.
  • Jane Street first reported a position in Agios Pharmaceuticals in Q3 2013 and has held it in 35 quarters since.
  • Jane Street's Agios Pharmaceuticals position peaked at $30.5M in Q4 2025.
  • 238 funds tracked by Wall St. Rank held Agios Pharmaceuticals as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.