Jane Street
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Jane Street’s Agios Pharmaceuticals AGIO Stock Holding History

Jane Street’s Portfolio AGIO Stock Details AGIO Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$1.66M Sell
49,100
-127,500
-72% -$3.61M ﹤0.01% 5439
2025
Q4 		$4.81M Buy
176,600
+118,600
+204% +$4.16M ﹤0.01% 3283
2025
Q3 		$2.33M Buy
+58,000
New +$2.18M ﹤0.01% 4659
2024
Q4 		– Sell
-8,300
Closed -$369K – 9294
2024
Q3 		$369K Sell
8,300
-17,400
-68% -$790K ﹤0.01% 7702
2024
Q2 		$1.11M Buy
25,700
+2,200
+9% +$79.4K ﹤0.01% 5571
2024
Q1 		$687K Buy
+23,500
New +$629K ﹤0.01% 6114
2023
Q3 		– Sell
-11,200
Closed -$317K – 8541
2023
Q2 		$317K Sell
11,200
-25,900
-70% -$645K ﹤0.01% 7037
2023
Q1 		$852K Sell
37,100
-54,000
-59% -$1.43M ﹤0.01% 5321
2022
Q4 		$2.56M Buy
91,100
+35,700
+64% +$1.01M ﹤0.01% 3469
2022
Q3 		$1.57M Sell
55,400
-13,700
-20% -$367K ﹤0.01% 4607
2022
Q2 		$1.53M Buy
69,100
+45,300
+190% +$1.02M ﹤0.01% 4662
2022
Q1 		$693K Sell
23,800
-96,900
-80% -$2.96M ﹤0.01% 6863
2021
Q4 		$3.97M Buy
120,700
+11,200
+10% +$451K ﹤0.01% 3209
2021
Q3 		$5.05M Buy
109,500
+13,600
+14% +$657K ﹤0.01% 2712
2021
Q2 		$5.29M Buy
95,900
+24,700
+35% +$1.38M ﹤0.01% 2546
2021
Q1 		$3.68M Sell
71,200
-36,300
-34% -$1.8M ﹤0.01% 2882
2020
Q4 		$4.66M Buy
107,500
+40,100
+59% +$1.59M ﹤0.01% 2226
2020
Q3 		$2.36M Sell
67,400
-65,900
-49% -$2.89M ﹤0.01% 2787
2020
Q2 		$7.13M Buy
133,300
+124,100
+1,349% +$5.75M 0.01% 1462
2020
Q1 		$326K Sell
9,200
-15,900
-63% -$735K ﹤0.01% 4111
2019
Q4 		$1.2M Buy
+25,100
New +$949K ﹤0.01% 2535
2018
Q4 		– Sell
-3,600
Closed -$278K – 4855
2018
Q3 		$278K Sell
3,600
-3,200
-47% -$257K ﹤0.01% 4308
2018
Q2 		$573K Buy
+6,800
New +$593K ﹤0.01% 3444
2017
Q3 		– Sell
-4,500
Closed -$232K – 4380
2017
Q2 		$232K Buy
+4,500
New +$230K ﹤0.01% 3879
2016
Q4 		– Sell
-18,200
Closed -$961K – 3974
2016
Q3 		$961K Buy
+18,200
New +$793K ﹤0.01% 2027

Other funds holding AGIO

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
AC
Armistice Capital New York $5.62B AUM 36.06% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
LCM
Lynx1 Capital Management San Juan, Puerto Rico $633M AUM 173.22% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
EAM
Erste Asset Management Vienna, Austria $12.9B AUM 52.69% 1-Year Est. Return
BNP Paribas Asset Management
BNP Paribas Asset Management Paris, France $86.1B AUM 29.11% 1-Year Est. Return

Jane Street's AGIO Position: Q1 2026 in Review

Jane Street reduced its Agios Pharmaceuticals (AGIO) stake by 39% in Q1 2026, selling an estimated $12.4M and leaving 685,240 shares worth $23.2M. The position accounts for ﹤0.01% of the portfolio, ranked #1647.

Jane Street first reported a position in AGIO in Q3 2013 and has held it in 34 quarters since. The position peaked at $30.5M in Q4 2025. 233 funds tracked by Wall St. Rank hold AGIO as of Q1 2026.

  • Jane Street held 685,240 shares of Agios Pharmaceuticals worth $23.2M as of Q1 2026.
  • Jane Street sold 435,810 Agios Pharmaceuticals shares in Q1 2026, an estimated $12.4M.
  • Agios Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #1647 holding.
  • Jane Street first reported a position in Agios Pharmaceuticals in Q3 2013 and has held it in 34 quarters since.
  • Jane Street's Agios Pharmaceuticals position peaked at $30.5M in Q4 2025.
  • 233 funds tracked by Wall St. Rank held Agios Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.