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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
101
Southern Company
SO
$106B
| $21.7K | 0.01% |
+236
| New | +$21.2K |
|
102
Constellation Energy
CEG
$98.7B
| $21.6K | 0.01% |
+67
| New | +$17.7K |
|
103
CME Group
CME
$94.3B
| $21.2K | 0.01% |
+77
| New | +$20.9K |
|
|
FISV
104
Fiserv Inc
FISV
$27.4B
| $21K | 0.01% |
+122
| New | +$22.1K |
|
105
Prologis
PLD
$134B
| $21K | 0.01% |
+200
| New | +$21K |
|
106
Trane Technologies
TT
$105B
| $21K | 0.01% |
+48
| New | +$18.9K |
|
107
Intel
INTC
$509B
| $20.9K | 0.01% |
+934
| New | +$19.4K |
|
108
Lockheed Martin
LMT
$140B
| $20.8K | 0.01% |
+45
| New | +$21.1K |
|
109
Bristol-Myers Squibb
BMY
$130B
| $20.3K | 0.01% |
+438
| New | +$21.5K |
|
110
Welltower
WELL
$166B
| $20.1K | 0.01% |
+131
| New | +$19.6K |
|
111
McKesson
MCK
$102B
| $19.8K | 0.01% |
+27
| New | +$19.1K |
|
112
Duke Energy
DUK
$96.3B
| $19.7K | 0.01% |
+167
| New | +$19.7K |
|
113
Cigna
CI
$73.3B
| $19.5K | 0.01% |
+59
| New | +$19K |
|
114
Elevance Health
ELV
$86.6B
| $19.4K | 0.01% |
+50
| New | +$20.1K |
|
115
KKR & Co
KKR
$99.5B
| $19.3K | 0.01% |
+145
| New | +$17K |
|
116
Parker-Hannifin
PH
$135B
| $18.9K | 0.01% |
+27
| New | +$17.1K |
|
117
Mondelez International
MDLZ
$79.4B
| $18.8K | 0.01% |
+279
| New | +$18.6K |
|
118
CVS Health
CVS
$121B
| $18.8K | 0.01% |
+272
| New | +$17.8K |
|
119
TransDigm Group
TDG
$68.3B
| $18.2K | 0.01% |
+12
| New | +$16.9K |
|
120
Cadence Design Systems
CDNS
$89B
| $18.2K | 0.01% |
+59
| New | +$17.2K |
|
121
Nike
NKE
$60.1B
| $18.1K | 0.01% |
+255
| New | +$15.3K |
|
122
DoorDash
DASH
$92.1B
| $18K | 0.01% |
+73
| New | +$14.6K |
|
123
Waste Management
WM
$90.5B
| $17.8K | 0.01% |
+78
| New | +$18.1K |
|
124
3M
MMM
$94.8B
| $17.8K | 0.01% |
+117
| New | +$16.7K |
|
125
Arthur J. Gallagher & Co
AJG
$65.5B
| $17.3K | 0.01% |
+54
| New | +$17.8K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.