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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
76
Micron Technology
MU
$1.03T
| $29.6K | 0.01% |
+240
| New | +$22.4K |
|
77
Stryker
SYK
$133B
| $29.3K | 0.01% |
+74
| New | +$27.7K |
|
78
Palo Alto Networks
PANW
$315B
| $29.3K | 0.01% |
+143
| New | +$26.6K |
|
79
Comcast
CMCSA
$90.4B
| $29.2K | 0.01% |
+817
| New | +$28.3K |
|
80
Capital One
COF
$136B
| $29.1K | 0.01% |
+137
| New | +$25.6K |
|
81
Deere & Co
DE
$167B
| $27.5K | 0.01% |
+54
| New | +$26.4K |
|
82
Danaher
DHR
$145B
| $27.3K | 0.01% |
+138
| New | +$26.8K |
|
83
Lowe's Companies
LOW
$121B
| $27.1K | 0.01% |
+122
| New | +$27.2K |
|
84
CrowdStrike
CRWD
$226B
| $27K | 0.01% |
+212
| New | +$23K |
|
85
Lam Research
LRCX
$408B
| $27K | 0.01% |
+277
| New | +$22K |
|
86
Automatic Data Processing
ADP
$107B
| $26.8K | 0.01% |
+87
| New | +$26.7K |
|
87
Amphenol
APH
$210B
| $25.8K | 0.01% |
+261
| New | +$21.3K |
|
88
Analog Devices
ADI
$187B
| $25.5K | 0.01% |
+107
| New | +$22.3K |
|
89
KLA
KLAC
$272B
| $25.1K | 0.01% |
+280
| New | +$21.1K |
|
90
ConocoPhillips
COP
$153B
| $24.7K | 0.01% |
+275
| New | +$24.7K |
|
91
T-Mobile US
TMUS
$190B
| $24.5K | 0.01% |
+103
| New | +$25.1K |
|
92
Vertex Pharmaceuticals
VRTX
$133B
| $24.5K | 0.01% |
+55
| New | +$25.3K |
|
93
Medtronic
MDT
$116B
| $24.1K | 0.01% |
+277
| New | +$23.5K |
|
94
Blackstone
BX
$110B
| $23.6K | 0.01% |
+158
| New | +$21.7K |
|
95
Chubb
CB
$132B
| $23.2K | 0.01% |
+80
| New | +$23K |
|
|
MRSH
96
Marsh
MRSH
$90.1B
| $23.2K | 0.01% |
+106
| New | +$23.9K |
|
97
Arista Networks
ANET
$265B
| $22.8K | 0.01% |
+223
| New | +$19.3K |
|
98
Intercontinental Exchange
ICE
$85B
| $22.8K | 0.01% |
+124
| New | +$21.3K |
|
99
Starbucks
SBUX
$124B
| $22.4K | 0.01% |
+245
| New | +$21.2K |
|
100
American Tower
AMT
$79.4B
| $22.1K | 0.01% |
+100
| New | +$21.6K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.