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HHMI
Howard Hughes Medical Institute Portfolio holdings
AUM
$416M
1-Year Est. Return
13.82%
This Fund
S&P 500
This Quarter
Est. Return
+10.63%
1 Year Est. Return
+13.82%
3 Year Est. Return
+59.34%
5 Year Est. Return
+48.21%
10 Year Est. Return
+227.75%
AUM
$251M
AUM Growth
+$48.7M
(+24%)
Cap. Flow
+$25.5M
Cap. Flow
% of AUM
10.17%
Top 10 Holdings %
Top 10 Hldgs %
97.11%
Holding
502
New
500
Increased
1
Reduced
–
Closed
1
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$15.6M |
| 2 |
Microsoft
MSFT
|
+$700K |
| 3 |
NVIDIA
NVDA
|
+$665K |
| 4 |
Apple
AAPL
|
+$653K |
| 5 |
Amazon
AMZN
|
+$403K |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
BIOA
BioAge Labs
BIOA
|
+$428K |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 1.55% |
| 2 | Financials | 0.62% |
| 3 | Consumer Discretionary | 0.47% |
| 4 | Communication Services | 0.44% |
| 5 | Healthcare | 0.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
51
Caterpillar
CAT
$393B
| $40K | 0.02% |
+103
| New | +$34.3K |
|
52
Verizon
VZ
$195B
| $39.3K | 0.02% |
+909
| New | +$39.4K |
|
53
PepsiCo
PEP
$189B
| $39.1K | 0.02% |
+296
| New | +$39.9K |
|
54
Qualcomm
QCOM
$171B
| $38.1K | 0.02% |
+239
| New | +$35.2K |
|
55
American Express
AXP
$232B
| $38K | 0.02% |
+119
| New | +$33.5K |
|
56
Morgan Stanley
MS
$342B
| $37.6K | 0.02% |
+267
| New | +$32.8K |
|
57
Adobe
ADBE
$103B
| $36.4K | 0.01% |
+94
| New | +$36.2K |
|
58
S&P Global
SPGI
$121B
| $35.9K | 0.01% |
+68
| New | +$33.9K |
|
59
Citigroup
C
$231B
| $34.5K | 0.01% |
+405
| New | +$29.3K |
|
60
Boston Scientific
BSX
$74.5B
| $34.2K | 0.01% |
+318
| New | +$32.2K |
|
61
Boeing
BA
$183B
| $33.9K | 0.01% |
+162
| New | +$30.6K |
|
62
Progressive
PGR
$121B
| $33.6K | 0.01% |
+126
| New | +$34.5K |
|
|
SCHW
63
Charles Schwab
SCHW
$189B
| $33.6K | 0.01% |
+368
| New | +$30.8K |
|
64
Thermo Fisher Scientific
TMO
$223B
| $33.2K | 0.01% |
+82
| New | +$34.3K |
|
65
Honeywell
HON
$74.6B
| $32.6K | 0.01% |
+149
| New | +$30.2K |
|
66
Blackrock
BLK
$180B
| $32.5K | 0.01% |
+31
| New | +$29.3K |
|
67
Amgen
AMGN
$225B
| $32.4K | 0.01% |
+116
| New | +$32.9K |
|
68
Applied Materials
AMAT
$435B
| $32K | 0.01% |
+175
| New | +$27.7K |
|
69
GE Vernova
GEV
$277B
| $31.2K | 0.01% |
+59
| New | +$24.6K |
|
70
NextEra Energy
NEE
$179B
| $30.8K | 0.01% |
+444
| New | +$30.8K |
|
71
Eaton
ETN
$179B
| $30.3K | 0.01% |
+85
| New | +$26.2K |
|
72
Union Pacific
UNP
$174B
| $29.9K | 0.01% |
+130
| New | +$28.9K |
|
73
TJX Companies
TJX
$169B
| $29.9K | 0.01% |
+242
| New | +$30.7K |
|
74
Gilead Sciences
GILD
$168B
| $29.8K | 0.01% |
+269
| New | +$28.6K |
|
75
Pfizer
PFE
$150B
| $29.6K | 0.01% |
+1,222
| New | +$28.5K |
|
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Howard Hughes Medical Institute's Q2 2025 Portfolio in Review
As of Q2 2025, Howard Hughes Medical Institute held 502 positions worth $251M, up 24% from $202M the previous quarter. Its ten largest holdings account for 97% of the portfolio.
Howard Hughes Medical Institute deployed $25.5M of net new capital in Q2 2025, opening 500 new positions and adding to 1 existing holding. Its largest new stake was Microsoft: 1,611 shares worth $801K.
By sector, the portfolio is most concentrated in Technology at 1.6% of assets, followed by Financials and Consumer Discretionary.
On the sell side, the most notable exit was BioAge Labs, an estimated $428K sold.
- Howard Hughes Medical Institute's largest Q2 2025 buy was Microsoft: 1,611 shares worth $801K.
- Howard Hughes Medical Institute added most to State Street SPDR S&P 500 ETF Trust in Q2 2025, an estimated $15.6M increase.
- Howard Hughes Medical Institute fully exited BioAge Labs in Q2 2025, selling an estimated $428K.
- Howard Hughes Medical Institute's ten largest holdings make up 97% of its $251M portfolio in Q2 2025.
- Howard Hughes Medical Institute opened 500 new positions and closed 1 in Q2 2025.
- Howard Hughes Medical Institute's portfolio value rose 24% quarter-over-quarter to $251M.
Based on Howard Hughes Medical Institute's 13F filing for Q2 2025, filed 14 Aug 2025.