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FCMI

Foresite Capital Management IV Portfolio holdings

AUM $290M
1-Year Est. Return 143.88%
This Fund
S&P 500
This Quarter Est. Return
+28.22%
1 Year Est. Return
+143.88%
3 Year Est. Return
+150.93%
5 Year Est. Return
+74.33%
10 Year Est. Return
AUM
$290M
AUM Growth
+$53.1M
Cap. Flow
-$4.71M
Cap. Flow %
-1.62%
Top 10 Hldgs %
100%
Holding
9
New
1
Increased
2
Reduced
Closed
3

Top Buys

Rank Stock Value
1
CYTK icon
Cytokinetics
CYTK
+$15.2M
2
CRNX
Crinetics Pharmaceuticals
CRNX
+$5.58M
3
RLAY icon
Relay Therapeutics
RLAY
+$3.63M

Top Sells

Rank Stock Value
1
LYEL icon
Lyell Immunopharma
LYEL
+$16.1M
2
ALEC icon
Alector
ALEC
+$8.36M
3
MAZE
Maze Therapeutics
MAZE
+$4.68M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
PHVS icon
1
Pharvaris
PHVS
$2.47B
$165M 56.95%
4,778,581
CYTK icon
2
Cytokinetics
CYTK
$10.1B
$60.9M 20.98%
714,695
+211,400
+42% +$15.2M
EIKN
3
Eikon Therapeutics
EIKN
$588M
$25.4M 8.74%
1,943,682
RLAY icon
4
Relay Therapeutics
RLAY
$4.17B
$23.4M 8.06%
1,250,000
+250,000
+25% +$3.63M
XENE icon
5
Xenon Pharmaceuticals
XENE
$5.79B
$9.66M 3.33%
160,000
CRNX
6
DELISTED
Crinetics Pharmaceuticals
CRNX
$5.61M 1.93%
+150,000
New +$5.58M
ALEC icon
7
Alector
ALEC
$275M
-3,887,200
Closed -$8.36M
LYEL icon
8
Lyell Immunopharma
LYEL
$352M
-800,399
Closed -$16.1M
MAZE
9
Maze Therapeutics
MAZE
$1.46B
-156,901
Closed -$4.68M

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Foresite Capital Management IV's Q2 2026 Portfolio in Review

As of Q2 2026, Foresite Capital Management IV held 9 positions worth $290M, up 22% from $237M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Foresite Capital Management IV's Q2 2026 filing shows 1 new, 2 increased and 3 closed positions. Its largest new stake was Crinetics Pharmaceuticals: 150,000 shares worth $5.61M. The largest sale was Lyell Immunopharma, an estimated $16.1M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • Foresite Capital Management IV's largest Q2 2026 buy was Crinetics Pharmaceuticals: 150,000 shares worth $5.61M.
  • Foresite Capital Management IV added most to Cytokinetics in Q2 2026, an estimated $15.2M increase.
  • Foresite Capital Management IV fully exited Lyell Immunopharma in Q2 2026, selling an estimated $16.1M.
  • Foresite Capital Management IV's ten largest holdings make up 100% of its $290M portfolio in Q2 2026.
  • Foresite Capital Management IV opened 1 new position and closed 3 in Q2 2026.
  • Foresite Capital Management IV's portfolio value rose 22% quarter-over-quarter to $290M.

Based on Foresite Capital Management IV's 13F filing for Q2 2026, filed 14 Aug 2026.