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FP

Flagship Pioneering Portfolio holdings

AUM $1.16B
1-Year Est. Return 67.93%
This Fund
S&P 500
This Quarter Est. Return
-22.71%
1 Year Est. Return
+67.93%
3 Year Est. Return
-39.17%
5 Year Est. Return
-45.89%
10 Year Est. Return
–
AUM
$236M
AUM Growth
-$98.5M
Cap. Flow
-$21.8M
Cap. Flow %
-9.24%
Top 10 Hldgs %
100%
Holding
5
New
–
Increased
–
Reduced
–
Closed
1

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
OMGA
Omega Therapeutics, Inc. Common Stock
OMGA
+$21.8M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MRNA icon
1
Moderna
MRNA
$22.2B
$131M 55.7%
4,632,149
– –
FHTX icon
2
Foghorn Therapeutics
FHTX
$294M
$46.3M 19.62%
12,674,120
– –
SANA icon
3
Sana Biotechnology
SANA
$946M
$42M 17.82%
25,001,856
– –
MCRB icon
4
Seres Therapeutics
MCRB
$49.1M
$16.2M 6.86%
1,155,852
– –
OMGA
5
DELISTED
Omega Therapeutics, Inc. Common Stock
OMGA
– –
-29,225,579
Closed -$21.8M

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Flagship Pioneering's Q1 2025 Portfolio in Review

As of Q1 2025, Flagship Pioneering held 5 positions worth $236M, down 29% from $334M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Flagship Pioneering withdrew a net $21.8M in Q1 2025, closing 1 position. Its most notable exit was Omega Therapeutics, Inc. Common Stock, an estimated $21.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • Flagship Pioneering fully exited Omega Therapeutics, Inc. Common Stock in Q1 2025, selling an estimated $21.8M.
  • Flagship Pioneering's ten largest holdings make up 100% of its $236M portfolio in Q1 2025.
  • Flagship Pioneering opened 0 new positions and closed 1 in Q1 2025.
  • Flagship Pioneering's portfolio value fell 29% quarter-over-quarter to $236M.

Based on Flagship Pioneering's 13F filing for Q1 2025, filed 15 May 2025.