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DCM

Driehaus Capital Management Portfolio holdings

AUM $13.6B
1-Year Est. Return 173.98%
This Fund
S&P 500
This Quarter Est. Return
+28.72%
1 Year Est. Return
+173.98%
3 Year Est. Return
+706.72%
5 Year Est. Return
+1,585.86%
10 Year Est. Return
+31,592.09%
AUM
$14.7B
AUM Growth
+$761M
Cap. Flow
-$934M
Cap. Flow %
-6.35%
Top 10 Hldgs %
16.56%
Holding
518
New
87
Increased
137
Reduced
150
Closed
114

Top Buys

Rank Stock Value
1
EOSE icon
Eos Energy Enterprises
EOSE
+$111M
2
RMBS icon
Rambus
RMBS
+$93.9M
3
PRAX icon
Praxis Precision Medicines
PRAX
+$80.5M
4
FMX icon
Fomento Económico Mexicano
FMX
+$65.4M
5
NU icon
Nu Holdings
NU
+$59.3M

Top Sells

Rank Stock Value
1
ALAB icon
Astera Labs
ALAB
+$138M
2
CVLT icon
Commault Systems
CVLT
+$120M
3
PL icon
Planet Labs
PL
+$84M
4
OLLI icon
Ollie's Bargain Outlet
OLLI
+$76.8M
5
CRDO icon
Credo Technology Group
CRDO
+$75.9M

Sector Composition

Rank Sector Weight
1 Healthcare 29.41%
2 Industrials 21.41%
3 Technology 18.1%
4 Consumer Discretionary 9.17%
5 Financials 9.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TSM icon
1
TSMC
TSM
$2.09T
$657M 4.47%
2,163,564
-79,824
-4% -$23.4M
CRNX icon
2
Crinetics Pharmaceuticals
CRNX
$8.86B
$297M 2.02%
6,387,740
-93,873
-1% -$4.18M
PRAX icon
3
Praxis Precision Medicines
PRAX
$9.07B
$275M 1.87%
933,061
+432,510
+86% +$80.5M
GH icon
4
Guardant Health
GH
$19.5B
$219M 1.49%
2,143,193
-9,122
-0.4% -$816K
XENE icon
5
Xenon Pharmaceuticals
XENE
$6.32B
$203M 1.38%
4,538,691
+369,577
+9% +$15.5M
PL icon
6
Planet Labs
PL
$7.3B
$168M 1.14%
8,511,620
-5,860,847
-41% -$84M
APGE icon
7
Apogee Therapeutics
APGE
$10.2B
$165M 1.12%
2,183,704
+25,202
+1% +$1.59M
EOSE icon
8
Eos Energy Enterprises
EOSE
$1.23B
$164M 1.11%
14,270,294
+7,704,785
+117% +$111M
SITM icon
9
SiTime
SITM
$16.6B
$146M 0.99%
412,873
-162,335
-28% -$50.8M
NTRA icon
10
Natera
NTRA
$37.5B
$143M 0.97%
625,912
+39,744
+7% +$8.29M
CCJ icon
11
Cameco
CCJ
$38.3B
$139M 0.95%
1,522,638
-224,624
-13% -$20.2M
FTAI icon
12
FTAI Aviation
FTAI
$22.2B
$138M 0.94%
700,525
+45,447
+7% +$7.74M
RYTM icon
13
Rhythm Pharmaceuticals
RYTM
$7B
$138M 0.93%
1,285,222
-98,553
-7% -$10.5M
HDB icon
14
HDFC Bank
HDB
$119B
$136M 0.92%
3,722,331
+516,986
+16% +$18.6M
BAP icon
15
Credicorp
BAP
$30.9B
$135M 0.92%
472,044
+29,891
+7% +$7.91M
SEPN
16
Septerna Inc
SEPN
$1.49B
$134M 0.91%
4,809,470
-110,426
-2% -$2.64M
NU icon
17
Nu Holdings
NU
$68.1B
$129M 0.88%
7,706,057
+3,689,298
+92% +$59.3M
BBIO icon
18
BridgeBio Pharma
BBIO
$16.5B
$129M 0.87%
1,680,972
+18,903
+1% +$1.24M
PI icon
19
Impinj
PI
$3.89B
$128M 0.87%
737,474
+222,974
+43% +$39.7M
CRS icon
20
Carpenter Technology
CRS
$30B
$127M 0.86%
403,296
+129,350
+47% +$38.9M
CW icon
21
Curtiss-Wright
CW
$27.7B
$127M 0.86%
229,703
-39,132
-15% -$21.8M
LITE icon
22
Lumentum
LITE
$59.4B
$126M 0.85%
341,048
-266,034
-44% -$68.3M
IBN icon
23
ICICI Bank
IBN
$106B
$121M 0.82%
4,063,452
-1,295,814
-24% -$39.8M
IDCC icon
24
InterDigital
IDCC
$6.68B
$119M 0.81%
375,174
+45,036
+14% +$15.9M
XMTR icon
25
Xometry
XMTR
$4.77B
$118M 0.8%
1,985,865
+488,780
+33% +$27.6M
1
2 3 4 5

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Driehaus Capital Management's Q4 2025 Portfolio in Review

As of Q4 2025, Driehaus Capital Management held 518 positions worth $14.7B, up 5.4% from $14B the previous quarter. Its ten largest holdings account for 17% of the portfolio.

Driehaus Capital Management withdrew a net $934M in Q4 2025, closing 114 positions and reducing 150 holdings. Its most notable exit was Commault Systems, an estimated $120M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 29% of assets, up from 20% a quarter earlier, followed by Industrials and Technology.

Against the trend, Driehaus Capital Management opened a new position in Rambus worth $87.7M.

  • Driehaus Capital Management's largest Q4 2025 buy was Rambus: 954,164 shares worth $87.7M.
  • Driehaus Capital Management added most to Eos Energy Enterprises in Q4 2025, an estimated $111M increase.
  • Driehaus Capital Management's biggest Q4 2025 reduction was Astera Labs, cutting an estimated $138M.
  • Driehaus Capital Management fully exited Commault Systems in Q4 2025, selling an estimated $120M.
  • Driehaus Capital Management's ten largest holdings make up 17% of its $14.7B portfolio in Q4 2025.
  • Driehaus Capital Management opened 87 new positions and closed 114 in Q4 2025.
  • Driehaus Capital Management's portfolio value rose 5.4% quarter-over-quarter to $14.7B.

Based on Driehaus Capital Management's 13F filing for Q4 2025, filed 17 Feb 2026.