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Deerfield Management Portfolio holdings
AUM
$8.48B
1-Year Est. Return
99.04%
This Fund
S&P 500
This Quarter
Est. Return
+6.55%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$8.48B
AUM Growth
+$646M
(+8.3%)
Cap. Flow
-$773M
Cap. Flow
% of AUM
-9.12%
Top 10 Holdings %
Top 10 Hldgs %
50.85%
Holding
160
New
9
Increased
15
Reduced
10
Closed
78
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Inspire Medical Systems
INSP
|
+$83.8M |
| 2 |
Syndax Pharmaceuticals
SNDX
|
+$82.1M |
| 3 |
Pfizer
PFE
|
+$80.9M |
| 4 |
Genmab
GMAB
|
+$73.8M |
| 5 |
Dianthus Therapeutics
DNTH
|
+$59.1M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Neurocrine Biosciences
NBIX
|
+$76.2M |
| 2 |
Revolution Medicines
RVMD
|
+$60.3M |
| 3 |
Phreesia
PHR
|
+$33.8M |
| 4 |
Ventas
VTR
|
+$27.4M |
| 5 |
Spyre Therapeutics
SYRE
|
+$23.3M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 84.65% |
| 2 | Consumer Discretionary | 0% |
| 3 | Consumer Staples | 0% |
| 4 | Financials | 0% |
| 5 | Industrials | 0% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
126
Phreesia
PHR
$662M
| – | – |
-1,999,045
| Closed | -$33.8M |
|
127
Insulet
PODD
$11.4B
| – | – |
-10,616
| Closed | -$3.02M |
|
128
RadNet
RDNT
$4.89B
| – | – |
-49,951
| Closed | -$3.56M |
|
129
Repligen
RGEN
$8.31B
| – | – |
-2,199
| Closed | -$360K |
|
130
ResMed
RMD
$28.9B
| – | – |
-10,104
| Closed | -$2.43M |
|
131
Revvity
RVTY
$12.3B
| – | – |
-10,323
| Closed | -$999K |
|
132
RxSight
RXST
$230M
| – | – |
-52,257
| Closed | -$545K |
|
133
Schrodinger
SDGR
$1.14B
| – | – |
-33,987
| Closed | -$608K |
|
134
Surgery Partners
SGRY
$2.09B
| – | – |
-112,623
| Closed | -$1.74M |
|
135
STAAR Surgical
STAA
$1.32B
| – | – |
-51,894
| Closed | -$1.2M |
|
136
Steris
STE
$21.2B
| – | – |
-1,352
| Closed | -$343K |
|
137
Stryker
SYK
$123B
| – | – |
-3,551
| Closed | -$1.25M |
|
|
138
Spyre Therapeutics
SYRE
$8.7B
| – | – |
-710,626
| Closed | -$23.3M |
|
139
Transmedics
TMDX
$2.56B
| – | – |
-25,492
| Closed | -$3.1M |
|
140
Tandem Diabetes Care
TNDM
$1.17B
| – | – |
-26,090
| Closed | -$573K |
|
141
Trupanion
TRUP
$1.16B
| – | – |
-66,438
| Closed | -$2.48M |
|
142
10x Genomics
TXG
$5.55B
| – | – |
-126,574
| Closed | -$2.06M |
|
143
UFP Technologies
UFPT
$1.87B
| – | – |
-5,098
| Closed | -$1.13M |
|
144
Veeva Systems
VEEV
$31.7B
| – | – |
-17,711
| Closed | -$3.95M |
|
145
Varex Imaging
VREX
$445M
| – | – |
-131,745
| Closed | -$1.53M |
|
|
146
Ventas
VTR
$46.7B
| – | – |
-354,000
| Closed | -$27.4M |
|
147
Petco
WOOF
$760M
| – | – |
-936,309
| Closed | -$2.63M |
|
148
Xeris Biopharma Holdings
XERS
$1.52B
| – | – |
-52,230
| Closed | -$410K |
|
149
Zoetis
ZTS
$32.1B
| – | – |
-5,698
| Closed | -$717K |
|
|
OMDA
150
Omada Health Inc
OMDA
$1.41B
| – | – |
-553,107
| Closed | -$8.73M |
|
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Deerfield Management's Q1 2026 Portfolio in Review
As of Q1 2026, Deerfield Management held 160 positions worth $8.48B, up 8.3% from $7.83B the previous quarter. Its ten largest holdings account for 51% of the portfolio.
Deerfield Management withdrew a net $773M in Q1 2026, closing 78 positions and reducing 10 holdings. Its most notable exit was Phreesia, an estimated $33.8M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 85% of assets, down from 87% a quarter earlier, followed by Consumer Discretionary and Consumer Staples.
Against the trend, Deerfield Management opened a new position in Syndax Pharmaceuticals worth $88.3M.
- Deerfield Management's largest Q1 2026 buy was Syndax Pharmaceuticals: 3,779,900 shares worth $88.3M.
- Deerfield Management added most to Inspire Medical Systems in Q1 2026, an estimated $83.8M increase.
- Deerfield Management's biggest Q1 2026 reduction was Neurocrine Biosciences, cutting an estimated $76.2M.
- Deerfield Management fully exited Phreesia in Q1 2026, selling an estimated $33.8M.
- Deerfield Management's ten largest holdings make up 51% of its $8.48B portfolio in Q1 2026.
- Deerfield Management opened 9 new positions and closed 78 in Q1 2026.
- Deerfield Management's portfolio value rose 8.3% quarter-over-quarter to $8.48B.
Based on Deerfield Management's 13F filing for Q1 2026, filed 15 May 2026.