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Deerfield Management

Deerfield Management Portfolio holdings

AUM $9.6B Turnover 24.47%
1-Year Est. Return 113.36%
This Fund
S&P 500
This Quarter Est. Return
+17.58%
1 Year Est. Return
+113.36%
3 Year Est. Return
+277.48%
5 Year Est. Return
+350.78%
10 Year Est. Return
+2,290.11%
AUM
$9.6B
AUM Growth
+$1.11B
Cap. Flow
-$1.32B
Cap. Flow %
-13.72%
Top 10 Hldgs %
53.17%
Holding
94
New
11
Increased
13
Reduced
11
Closed
12
Avg Time Held
1.9 years
Top 10 Avg Time Held
1.1 years
Top 20 Avg Time Held
1.6 years

Sector Composition

Rank Sector Weight
1 Healthcare 83.76%
2 Miscellaneous 16.24%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
DAWN icon
76
DELISTED
Day One Biopharmaceuticals
DAWN
– –
-3,723,131
Closed -$79.8M –
EHAB icon
77
DELISTED
Enhabit
EHAB
– –
-4,747,746
Closed -$66.9M –
KYMR icon
78
Kymera Therapeutics
KYMR
$9.31B
– –
-561,170
Closed -$46.7M –
MYGN icon
79
Myriad Genetics
MYGN
$556M
– –
-505
Closed -$2.27K –
NBIX icon
80
Neurocrine Biosciences
NBIX
$14.5B
– –
-610,000
Closed -$80.4M –
HLSQ
81
Tessera Defense and Homeland Security Inc.
HLSQ
$2.4M
– –
-13,127
Closed -$493K –
QSIAW
82
DELISTED
Quantum-Si Inc Warrant
QSIAW
– –
-333,333
Closed -$36.2K –
TSHA icon
83
Taysha Gene Therapies
TSHA
$1.31B
– –
-2,722,165
Closed -$12.2M –
MANE icon
84
Veradermics Inc
MANE
$5.79B
– –
-5,000
Closed -$316K –

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Deerfield Management's Q2 2026 Portfolio in Review

As of Q2 2026, Deerfield Management held 94 positions worth $9.6B, up 13% from $8.48B the previous quarter. Its ten largest holdings account for 53% of the portfolio.

Deerfield Management withdrew a net $1.32B in Q2 2026, closing 12 positions and reducing 11 holdings. Its most notable exit was Catalyst Pharmaceutical, an estimated $97.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, down from 85% a quarter earlier, followed by Miscellaneous.

Against the trend, Deerfield Management opened a new position in Mineralys Therapeutics worth $107M.

  • Deerfield Management's largest Q2 2026 buy was Mineralys Therapeutics: 3,958,000 shares worth $107M.
  • Deerfield Management added most to Genmab in Q2 2026, an estimated $117M increase.
  • Deerfield Management's biggest Q2 2026 reduction was Cogent Biosciences, cutting an estimated $141M.
  • Deerfield Management fully exited Catalyst Pharmaceutical in Q2 2026, selling an estimated $97.6M.
  • Deerfield Management's ten largest holdings make up 53% of its $9.6B portfolio in Q2 2026.
  • Deerfield Management opened 11 new positions and closed 12 in Q2 2026.
  • Deerfield Management's portfolio value rose 13% quarter-over-quarter to $9.6B.

Based on Deerfield Management's 13F filing for Q2 2026, filed 14 Aug 2026.