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Deerfield Management Portfolio holdings
AUM
$8.48B
1-Year Est. Return
99.04%
This Fund
S&P 500
This Quarter
Est. Return
+6.55%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$8.48B
AUM Growth
+$646M
(+8.3%)
Cap. Flow
-$773M
Cap. Flow
% of AUM
-9.12%
Top 10 Holdings %
Top 10 Hldgs %
50.85%
Holding
160
New
9
Increased
15
Reduced
10
Closed
78
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Inspire Medical Systems
INSP
|
+$83.8M |
| 2 |
Syndax Pharmaceuticals
SNDX
|
+$82.1M |
| 3 |
Pfizer
PFE
|
+$80.9M |
| 4 |
Genmab
GMAB
|
+$73.8M |
| 5 |
Dianthus Therapeutics
DNTH
|
+$59.1M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Neurocrine Biosciences
NBIX
|
+$76.2M |
| 2 |
Revolution Medicines
RVMD
|
+$60.3M |
| 3 |
Phreesia
PHR
|
+$33.8M |
| 4 |
Ventas
VTR
|
+$27.4M |
| 5 |
Spyre Therapeutics
SYRE
|
+$23.3M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 84.65% |
| 2 | Consumer Discretionary | 0% |
| 3 | Consumer Staples | 0% |
| 4 | Financials | 0% |
| 5 | Industrials | 0% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
101
DexCom
DXCM
$29.6B
| – | – |
-32,943
| Closed | -$2.19M |
|
102
Encompass Health
EHC
$11.1B
| – | – |
-15,259
| Closed | -$1.62M |
|
103
Enovis
ENOV
$1.56B
| – | – |
-127,270
| Closed | -$3.39M |
|
104
Edgewise Therapeutics
EWTX
$4.28B
| – | – |
-765,694
| Closed | -$19M |
|
105
National Vision
EYE
$1.66B
| – | – |
-10,284
| Closed | -$266K |
|
106
GoodRx Holdings
GDRX
$1.06B
| – | – |
-660,133
| Closed | -$1.79M |
|
107
Healthcare Services Group
HCSG
$1.74B
| – | – |
-21,259
| Closed | -$406K |
|
108
HealthEquity
HQY
$8.17B
| – | – |
-16,231
| Closed | -$1.49M |
|
109
Harrow
HROW
$1.74B
| – | – |
-8,693
| Closed | -$426K |
|
110
Integra LifeSciences
IART
$1.5B
| – | – |
-39,209
| Closed | -$487K |
|
111
iRhythm Holdings
IRTC
$3.64B
| – | – |
-12,099
| Closed | -$2.15M |
|
112
Intuitive Surgical
ISRG
$122B
| – | – |
-483
| Closed | -$274K |
|
113
Integer Holdings
ITGR
$3.24B
| – | – |
-13,326
| Closed | -$1.05M |
|
114
OrthoPediatrics
KIDS
$493M
| – | – |
-144,220
| Closed | -$2.56M |
|
115
Kenvue
KVUE
$36.4B
| – | – |
-65,344
| Closed | -$1.13M |
|
116
Labcorp
LH
$23.2B
| – | – |
-13,825
| Closed | -$3.47M |
|
117
LeMaitre Vascular
LMAT
$2.32B
| – | – |
-25,815
| Closed | -$2.09M |
|
|
MASI
118
DELISTED
Masimo
MASI
| – | – |
-16,147
| Closed | -$2.1M |
|
119
MiMedx Group
MDXG
$640M
| – | – |
-160,419
| Closed | -$1.09M |
|
120
Maximus
MMS
$3.06B
| – | – |
-16,606
| Closed | -$1.43M |
|
121
Merit Medical Systems
MMSI
$4.41B
| – | – |
-18,798
| Closed | -$1.66M |
|
122
PUT
Moderna
MRNA
$24.5B
| – | – |
-1,000,000
| Closed | -$29.5M |
|
123
National Healthcare
NHC
$3.56B
| – | – |
-12,085
| Closed | -$1.66M |
|
|
NUVB.WS
124
DELISTED
Nuvation Bio Inc Warrants
NUVB.WS
| – | – |
-166,666
| Closed | -$55K |
|
125
Prestige Consumer Healthcare
PBH
$2.36B
| – | – |
-69,669
| Closed | -$4.3M |
|
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Deerfield Management's Q1 2026 Portfolio in Review
As of Q1 2026, Deerfield Management held 160 positions worth $8.48B, up 8.3% from $7.83B the previous quarter. Its ten largest holdings account for 51% of the portfolio.
Deerfield Management withdrew a net $773M in Q1 2026, closing 78 positions and reducing 10 holdings. Its most notable exit was Phreesia, an estimated $33.8M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 85% of assets, down from 87% a quarter earlier, followed by Consumer Discretionary and Consumer Staples.
Against the trend, Deerfield Management opened a new position in Syndax Pharmaceuticals worth $88.3M.
- Deerfield Management's largest Q1 2026 buy was Syndax Pharmaceuticals: 3,779,900 shares worth $88.3M.
- Deerfield Management added most to Inspire Medical Systems in Q1 2026, an estimated $83.8M increase.
- Deerfield Management's biggest Q1 2026 reduction was Neurocrine Biosciences, cutting an estimated $76.2M.
- Deerfield Management fully exited Phreesia in Q1 2026, selling an estimated $33.8M.
- Deerfield Management's ten largest holdings make up 51% of its $8.48B portfolio in Q1 2026.
- Deerfield Management opened 9 new positions and closed 78 in Q1 2026.
- Deerfield Management's portfolio value rose 8.3% quarter-over-quarter to $8.48B.
Based on Deerfield Management's 13F filing for Q1 2026, filed 15 May 2026.