DS
CSTL icon

David Shaw’s Castle Biosciences CSTL Stock Holding History

David Shaw’s Portfolio CSTL Stock Details CSTL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$2.69M Sell
112,789
-99,177
-47% -$2.21M ﹤0.01% 2947
2026
Q1 		$5.2M Buy
211,966
+52,257
+33% +$1.71M ﹤0.01% 2141
2025
Q4 		$6.21M Buy
159,709
+67,095
+72% +$2.16M ﹤0.01% 2129
2025
Q3 		$2.11M Sell
92,614
-55,576
-38% -$1.13M ﹤0.01% 2942
2025
Q2 		$3.03M Sell
148,190
-40,987
-22% -$759K ﹤0.01% 2421
2025
Q1 		$3.79M Buy
189,177
+98,614
+109% +$2.44M ﹤0.01% 2112
2024
Q4 		$2.41M Buy
+90,563
New +$2.76M ﹤0.01% 2583
2024
Q2 		– Sell
-13,382
Closed -$296K – 4536
2024
Q1 		$296K Sell
13,382
-38,982
-74% -$848K ﹤0.01% 3733
2023
Q4 		$1.13M Buy
+52,364
New +$922K ﹤0.01% 3057
2023
Q1 		– Sell
-28,937
Closed -$681K – 4525
2022
Q4 		$681K Buy
28,937
+1,405
+5% +$32.6K ﹤0.01% 3683
2022
Q3 		$718K Buy
+27,532
New +$772K ﹤0.01% 3818
2021
Q4 		– Sell
-7,104
Closed -$472K – 5458
2021
Q3 		$472K Buy
+7,104
New +$500K ﹤0.01% 4118
2021
Q2 		– Sell
-19,153
Closed -$1.31M – 4780
2021
Q1 		$1.31M Buy
19,153
+64
+0.3% +$4.81K ﹤0.01% 2905
2020
Q4 		$1.28M Buy
19,089
+10,492
+122% +$569K ﹤0.01% 2867
2020
Q3 		$442K Sell
8,597
-8,854
-51% -$394K ﹤0.01% 3285
2020
Q2 		$658K Buy
+17,451
New +$596K ﹤0.01% 3181

Other funds holding CSTL

BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
RI
RTW Investments New York $11.7B AUM 174.13% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return
California State Teachers Retirement System (CalSTRS)
California State Teachers Retirement System (CalSTRS) West Sacramento, California $782B AUM 28.39% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
Acadian Asset Management
Acadian Asset Management Boston, Massachusetts $84.2B AUM 55.88% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Allianz Asset Management
Allianz Asset Management Munich, Germany $112B AUM 36.28% 1-Year Est. Return
SPPAM
Summit Partners Public Asset Management Boston, Massachusetts $5.69B AUM 259.25% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

David Shaw's CSTL Position: Q2 2026 in Review

David Shaw reduced its Castle Biosciences (CSTL) stake by 47% in Q2 2026, selling an estimated $2.21M and leaving 112,789 shares worth $2.69M. The position accounts for ﹤0.01% of the portfolio, ranked #2947.

David Shaw first reported a position in CSTL in Q2 2020 and has held it in 16 quarters since. The position peaked at $6.21M in Q4 2025. 176 funds tracked by Wall St. Rank hold CSTL as of Q2 2026.

  • David Shaw held 112,789 shares of Castle Biosciences worth $2.69M as of Q2 2026.
  • David Shaw sold 99,177 Castle Biosciences shares in Q2 2026, an estimated $2.21M.
  • Castle Biosciences made up ﹤0.01% of David Shaw's portfolio in Q2 2026, its #2947 holding.
  • David Shaw first reported a position in Castle Biosciences in Q2 2020 and has held it in 16 quarters since.
  • David Shaw's Castle Biosciences position peaked at $6.21M in Q4 2025.
  • 176 funds tracked by Wall St. Rank held Castle Biosciences as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.