Castle BiosciencesCSTL
About: Castle Biosciences Inc is a molecular diagnostics company. The group provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), and uveal melanoma. The product portfolio of the company includes DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test; DecisionDx-SCC, a risk stratification test for cutaneous squamous cell carcinoma; MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a test to predict future development of progression of high-grade dysplasia and/or esophageal cancer. It also provides DecisionDx-UM, a risk stratification GEP test. The company also offers its products to the skin cancer and gastroenterology markets.
Employees: 784
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
79% more call options, than puts
Call options by funds: $200K | Put options by funds: $112K
39% more repeat investments, than reductions
Existing positions increased: 75 | Existing positions reduced: 54
0% more funds holding in top 10
Funds holding in top 10: 2 [Q4 2024] → 2 (+0) [Q1 2025]
3.92% less ownership
Funds ownership: 94.38% [Q4 2024] → 90.47% (-3.92%) [Q1 2025]
9% less funds holding
Funds holding: 196 [Q4 2024] → 179 (-17) [Q1 2025]
27% less capital invested
Capital invested by funds: $705M [Q4 2024] → $515M (-$190M) [Q1 2025]
30% less first-time investments, than exits
New positions opened: 30 | Existing positions closed: 43
Research analyst outlook
3 Wall Street Analysts provided 1 year price targets over the past 3 months
3 analyst ratings
Scotiabank Sung Ji Nam | 113%upside $40 | Sector Outperform Maintained | 21 May 2025 |
Lake Street Thomas Flaten | 87%upside $35 | Buy Maintained | 6 May 2025 |
Canaccord Genuity Kyle Mikson | 97%upside $37 | Buy Maintained | 6 May 2025 |
Financial journalist opinion
Based on 4 articles about CSTL published over the past 30 days









