DS
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David Shaw’s Annexon ANNX Stock Holding History

David Shaw’s Portfolio ANNX Stock Details ANNX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$1.51M Sell
265,284
-437,515
-62% -$2.42M ﹤0.01% 3434
2026
Q1 		$3.89M Sell
702,799
-343,422
-33% -$1.93M ﹤0.01% 2374
2025
Q4 		$5.25M Buy
+1,046,221
New +$4M ﹤0.01% 2254
2024
Q4 		– Sell
-81,411
Closed -$482K – 4383
2024
Q3 		$482K Sell
81,411
-10,674
-12% -$63.3K ﹤0.01% 3726
2024
Q2 		$451K Sell
92,085
-287,169
-76% -$1.49M ﹤0.01% 3691
2024
Q1 		$2.72M Buy
+379,254
New +$1.97M ﹤0.01% 2389
2023
Q2 		– Sell
-27,136
Closed -$104K – 4215
2023
Q1 		$104K Sell
27,136
-51,373
-65% -$283K ﹤0.01% 3976
2022
Q4 		$406K Buy
78,509
+30,484
+63% +$167K ﹤0.01% 3965
2022
Q3 		$297K Buy
48,025
+9,699
+25% +$52.4K ﹤0.01% 4304
2022
Q2 		$144K Sell
38,326
-125,053
-77% -$382K ﹤0.01% 4654
2022
Q1 		$446K Buy
+163,379
New +$1.01M ﹤0.01% 4440

Other funds holding ANNX

California State Teachers Retirement System (CalSTRS)
California State Teachers Retirement System (CalSTRS) West Sacramento, California $782B AUM 28.39% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
RG
Redmile Group San Francisco, California $1.49B AUM 208.7% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $32.4B AUM 58.5% 1-Year Est. Return
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
MCO
MAK Capital One New York $714M AUM 68.07% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $1.15T AUM 47.82% 1-Year Est. Return

David Shaw's ANNX Position: Q2 2026 in Review

David Shaw reduced its Annexon (ANNX) stake by 62% in Q2 2026, selling an estimated $2.42M and leaving 265,284 shares worth $1.51M. The position accounts for ﹤0.01% of the portfolio, ranked #3434.

David Shaw first reported a position in ANNX in Q1 2022 and has held it in 11 quarters since. The position peaked at $5.25M in Q4 2025. 215 funds tracked by Wall St. Rank hold ANNX as of Q2 2026.

  • David Shaw held 265,284 shares of Annexon worth $1.51M as of Q2 2026.
  • David Shaw sold 437,515 Annexon shares in Q2 2026, an estimated $2.42M.
  • Annexon made up ﹤0.01% of David Shaw's portfolio in Q2 2026, its #3434 holding.
  • David Shaw first reported a position in Annexon in Q1 2022 and has held it in 11 quarters since.
  • David Shaw's Annexon position peaked at $5.25M in Q4 2025.
  • 215 funds tracked by Wall St. Rank held Annexon as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.