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DGM

Darwin Global Management Portfolio holdings

AUM $3.77B
1-Year Est. Return 307.72%
This Fund
S&P 500
This Quarter Est. Return
+37.19%
1 Year Est. Return
+307.72%
3 Year Est. Return
+2,873.14%
5 Year Est. Return
+48,315.58%
10 Year Est. Return
AUM
$859M
AUM Growth
+$108M
Cap. Flow
+$44.8M
Cap. Flow %
5.22%
Top 10 Hldgs %
100%
Holding
17
New
5
Increased
1
Reduced
3
Closed
8

Top Buys

Rank Stock Value
1
CYTK icon
Cytokinetics
CYTK
+$276M
2
INSM icon
Insmed
INSM
+$137M
3
GERN icon
Geron
GERN
+$93.2M
4
CRBP icon
Corbus Pharmaceuticals
CRBP
+$13.7M
5
RNAM
Avidity Biosciences
RNAM
+$5.74M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
CYTK icon
1
Cytokinetics
CYTK
$10.9B
$246M 28.63%
+4,575,558
New +$276M
INSM icon
2
Insmed
INSM
$23.5B
$237M 27.58%
+3,541,095
New +$137M
PCVX icon
3
Vaxcyte
PCVX
$8.12B
$164M 19.07%
2,080,946
-669,858
-24% -$45.6M
GERN icon
4
Geron
GERN
$924M
$106M 12.35%
+23,915,480
New +$93.2M
KROS icon
5
Keros Therapeutics
KROS
$211M
$68.8M 8%
1,525,902
+89,952
+6% +$4.83M
CRBP icon
6
Corbus Pharmaceuticals
CRBP
$167M
$14.3M 1.66%
+325,140
New +$13.7M
SYRE icon
7
Spyre Therapeutics
SYRE
$8.7B
$10.3M 1.19%
452,040
-21,160
-4% -$714K
RNAM
8
DELISTED
Avidity Biosciences
RNAM
$8.11M 0.94%
+200,000
New +$5.74M
ELEV
9
DELISTED
Elevation Oncology
ELEV
$4.81M 0.56%
1,916,290
-416,638
-18% -$1.57M
APGE icon
10
Apogee Therapeutics
APGE
$10.1B
-832,198
Closed -$55.3M
BEAM icon
11
Beam Therapeutics
BEAM
$2.83B
-2,119,598
Closed -$70M
BHVN icon
12
Biohaven
BHVN
$2.32B
-1,476,974
Closed -$80.8M
MRK icon
13
Merck
MRK
$315B
-79,600
Closed -$10.5M
NUVL
14
DELISTED
Nuvalent
NUVL
-1,436,964
Closed -$108M
TRML
15
DELISTED
Tourmaline Bio
TRML
-465,000
Closed -$10.6M
XNCR icon
16
Xencor
XNCR
$1.3B
-1,109,650
Closed -$24.6M
ALPN
17
DELISTED
Alpine Immune Sciences Inc
ALPN
-1,982,016
Closed -$78.6M

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Darwin Global Management's Q2 2024 Portfolio in Review

As of Q2 2024, Darwin Global Management held 17 positions worth $859M, up 14% from $751M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Darwin Global Management deployed $44.8M of net new capital in Q2 2024, opening 5 new positions and adding to 1 existing holding. Its largest new stake was Cytokinetics: 4,575,558 shares worth $246M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the largest reduction was Vaxcyte, an estimated $45.6M trimmed.

  • Darwin Global Management's largest Q2 2024 buy was Cytokinetics: 4,575,558 shares worth $246M.
  • Darwin Global Management added most to Keros Therapeutics in Q2 2024, an estimated $4.83M increase.
  • Darwin Global Management's biggest Q2 2024 reduction was Vaxcyte, cutting an estimated $45.6M.
  • Darwin Global Management fully exited Nuvalent in Q2 2024, selling an estimated $108M.
  • Darwin Global Management's ten largest holdings make up 100% of its $859M portfolio in Q2 2024.
  • Darwin Global Management opened 5 new positions and closed 8 in Q2 2024.
  • Darwin Global Management's portfolio value rose 14% quarter-over-quarter to $859M.

Based on Darwin Global Management's 13F filing for Q2 2024, filed 14 Aug 2024.