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DGM

Darwin Global Management Portfolio holdings

AUM $3.77B
1-Year Est. Return 307.72%
This Fund
S&P 500
This Quarter Est. Return
+53.03%
1 Year Est. Return
+307.72%
3 Year Est. Return
+2,873.14%
5 Year Est. Return
+48,315.58%
10 Year Est. Return
AUM
$751M
AUM Growth
+$242M
Cap. Flow
+$161M
Cap. Flow %
21.45%
Top 10 Hldgs %
97.18%
Holding
17
New
9
Increased
3
Reduced
Closed
5

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
PCVX icon
1
Vaxcyte
PCVX
$8.12B
$188M 25.02%
2,750,804
+2,170,845
+374% +$150M
NUVL
2
DELISTED
Nuvalent
NUVL
$108M 14.36%
1,436,964
+1,379,266
+2,390% +$110M
KROS icon
3
Keros Therapeutics
KROS
$211M
$95.1M 12.66%
1,435,950
+375,523
+35% +$22.3M
BHVN icon
4
Biohaven
BHVN
$2.32B
$80.8M 10.75%
+1,476,974
New +$73.1M
ALPN
5
DELISTED
Alpine Immune Sciences Inc
ALPN
$78.6M 10.46%
+1,982,016
New +$58.5M
BEAM icon
6
Beam Therapeutics
BEAM
$2.83B
$70M 9.32%
+2,119,598
New +$66M
APGE icon
7
Apogee Therapeutics
APGE
$10.1B
$55.3M 7.36%
+832,198
New +$36.3M
XNCR icon
8
Xencor
XNCR
$1.3B
$24.6M 3.27%
+1,109,650
New +$24M
SYRE icon
9
Spyre Therapeutics
SYRE
$8.7B
$17.9M 2.39%
+473,200
New +$13.7M
ELEV
10
DELISTED
Elevation Oncology
ELEV
$12M 1.59%
+2,332,928
New +$7.56M
TRML
11
DELISTED
Tourmaline Bio
TRML
$10.6M 1.42%
+465,000
New +$16.4M
MRK icon
12
Merck
MRK
$315B
$10.5M 1.4%
+79,600
New +$9.81M
CYTK icon
13
Cytokinetics
CYTK
$10.9B
-600,000
Closed -$50.1M
MLTX icon
14
MoonLake Immunotherapeutics
MLTX
$1.64B
-1,039,289
Closed -$62.8M
SWTX
15
DELISTED
SpringWorks Therapeutics
SWTX
-192,734
Closed -$7.03M
TGTX icon
16
TG Therapeutics
TGTX
$8.4B
-4,046,598
Closed -$69.1M
AMAM
17
DELISTED
Ambrx Biopharma Inc
AMAM
-16,688,636
Closed -$238M

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Darwin Global Management's Q1 2024 Portfolio in Review

As of Q1 2024, Darwin Global Management held 17 positions worth $751M, up 47% from $509M the previous quarter. Its ten largest holdings account for 97% of the portfolio.

Darwin Global Management deployed $161M of net new capital in Q1 2024, opening 9 new positions and adding to 3 existing holdings. Its largest new stake was Biohaven: 1,476,974 shares worth $80.8M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

On the sell side, the most notable exit was Ambrx Biopharma Inc, an estimated $238M sold.

  • Darwin Global Management's largest Q1 2024 buy was Biohaven: 1,476,974 shares worth $80.8M.
  • Darwin Global Management added most to Vaxcyte in Q1 2024, an estimated $150M increase.
  • Darwin Global Management fully exited Ambrx Biopharma Inc in Q1 2024, selling an estimated $238M.
  • Darwin Global Management's ten largest holdings make up 97% of its $751M portfolio in Q1 2024.
  • Darwin Global Management opened 9 new positions and closed 5 in Q1 2024.
  • Darwin Global Management's portfolio value rose 47% quarter-over-quarter to $751M.

Based on Darwin Global Management's 13F filing for Q1 2024, filed 15 May 2024.