D.E. Shaw & Co
ONC

D.E. Shaw & Co’s BeOne Medicines Ltd ONC Stock Holding History

D.E. Shaw & Co’s Portfolio ONC Stock Details ONC Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-158,200
Closed -$48M – 5006
2025
Q2 		$38.3M Buy
158,200
+17,626
+13% +$4.32M 0.03% 691
2025
Q1 		$38.3M Buy
+140,574
New +$32.9M 0.03% 593
2024
Q1 		– Sell
-2,727
Closed -$492K – 4819
2023
Q4 		$492K Buy
+2,727
New +$493K ﹤0.01% 3519
2021
Q1 		– Sell
-51,120
Closed -$13.2M – 4554
2020
Q4 		$13.2M Buy
+51,120
New +$14.1M 0.01% 1206
2019
Q1 		– Sell
-5,256
Closed -$737K – 3988
2018
Q4 		$737K Buy
5,256
+4,032
+329% +$535K ﹤0.01% 2863
2018
Q3 		$211K Sell
1,224
-2,094
-63% -$352K ﹤0.01% 3522
2018
Q2 		$510K Buy
+3,318
New +$592K ﹤0.01% 3107
2018
Q1 		– Sell
-6,866
Closed -$930K – 3826
2017
Q4 		$671K Sell
6,866
-13,173
-66% -$1.21M ﹤0.01% 2808
2017
Q3 		$2.07M Buy
+20,039
New +$1.49M ﹤0.01% 1996
2017
Q2 		– Sell
-29,273
Closed -$1.07M – 3574
2017
Q1 		$1.07M Buy
+29,273
New +$1.07M ﹤0.01% 2260

Other funds holding ONC

BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Primecap Management
Primecap Management Pasadena, California $169B AUM 114.72% 1-Year Est. Return
Capital International Investors
Capital International Investors Los Angeles, California $484B AUM 34.9% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Capital World Investors
Capital World Investors Los Angeles, California $846B AUM 46.74% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return
Temasek Holdings
Temasek Holdings Singapore $37.3B AUM 12.6% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Millennium Management
Millennium Management New York $276B AUM 44.8% 1-Year Est. Return

D.E. Shaw & Co's ONC Position: Q3 2025 in Review

D.E. Shaw & Co sold out of BeOne Medicines Ltd (ONC) in Q3 2025, closing a stake of 158,200 shares — an estimated $48M sold.

D.E. Shaw & Co first reported a position in ONC in Q1 2017 and held it in 10 quarters. The position peaked at $38.3M in Q2 2025. 266 funds tracked by Wall St. Rank hold ONC as of Q3 2025.

  • D.E. Shaw & Co reported no remaining BeOne Medicines Ltd position as of Q3 2025 after selling out during the quarter.
  • D.E. Shaw & Co sold 158,200 BeOne Medicines Ltd shares in Q3 2025, an estimated $48M.
  • D.E. Shaw & Co first reported a position in BeOne Medicines Ltd in Q1 2017 and held it in 10 quarters.
  • D.E. Shaw & Co's BeOne Medicines Ltd position peaked at $38.3M in Q2 2025.
  • 266 funds tracked by Wall St. Rank held BeOne Medicines Ltd as of Q3 2025.

Based on D.E. Shaw & Co's 13F filing for Q3 2025, filed 14 Nov 2025.