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ONC

BeOne Medicines Ltd

244 hedge funds and large institutions have $8.34B invested in BeOne Medicines Ltd in 2025 Q2 according to their latest regulatory filings, with 28 funds opening new positions, 91 increasing their positions, 83 reducing their positions, and 50 closing their positions.

New
Increased
Maintained
Reduced
Closed

28.12% more ownership

Funds ownership: 3.32%31.44% (+28%)

11% more call options, than puts

Call options by funds: $36.7M | Put options by funds: $33.2M

10% more repeat investments, than reductions

Existing positions increased: 91 | Existing positions reduced: 83

9% less funds holding

Funds holding: 267244 (-23)

11% less funds holding in top 10

Funds holding in top 10: 98 (-1)

28% less capital invested

Capital invested by funds: $11.6B → $8.34B (-$3.24B)

44% less first-time investments, than exits

New positions opened: 28 | Existing positions closed: 50

Holders
244
Holders Change
-23
Holders Change %
-8.61%
% of All Funds
3.21%
Holding in Top 10
8
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-11.11%
% of All Funds
0.11%
New
28
Increased
91
Reduced
83
Closed
50
Calls
$36.7M
Puts
$33.2M
Net Calls
+$3.51M
Net Calls Change
+$2.37M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$2.13B
Primecap Management
2
Primecap Management
California
$1.23B +$8.04M +32,775 +0.6%
Capital International Investors
3
Capital International Investors
California
$1.18B -$50.5M -205,964 -4%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$835M -$928K -3,783 -0.1%
HA
5
HHLR Advisors
Cayman Islands
$250M
T. Rowe Price Associates
6
T. Rowe Price Associates
Maryland
$247M -$415M -1,693,291 -62%
Temasek Holdings
7
Temasek Holdings
Singapore
$245M +$4.1M +16,713 +2%
Citadel Advisors
8
Citadel Advisors
Florida
$130M -$109M -445,005 -45%
SL
9
Siren LLC
Connecticut
$123M +$2.77M +11,301 +2%
BlackRock
10
BlackRock
New York
$121M -$19.9M -81,101 -14%
Marshall Wace
11
Marshall Wace
United Kingdom
$113M -$2.34M -9,553 -2%
PBA
12
Paradigm Biocapital Advisors
New York
$84.2M -$78M -318,237 -48%
CII
13
Capital International Inc
California
$83.6M -$22.5M -91,823 -21%
N
14
Nuveen
North Carolina
$83.3M -$550K -2,244 -0.6%
Baird Financial Group
15
Baird Financial Group
Wisconsin
$82.9M +$16.7M +68,046 +25%
Connor, Clark & Lunn Investment Management (CC&L)
16
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$73.3M +$2.79M +11,393 +4%
CS
17
Candriam SCA
Luxembourg
$67.9M -$1.38M -5,607 -2%
Bank of America
18
Bank of America
North Carolina
$67.7M -$3.26M -13,294 -5%
Artisan Partners
19
Artisan Partners
Wisconsin
$65.4M -$4.23M -17,247 -6%
Morgan Stanley
20
Morgan Stanley
New York
$65M -$35.2M -143,455 -35%
Man Group
21
Man Group
United Kingdom
$59M +$22.1M +90,038 +59%
PIF
22
Public Investment Fund
Saudi Arabia
$55M -$31.2M -127,208 -36%
Millennium Management
23
Millennium Management
New York
$48.7M +$3.54M +14,445 +8%
DCM
24
Driehaus Capital Management
Illinois
$48M +$4.23M +17,247 +10%
UBS Group
25
UBS Group
Switzerland
$43.9M +$28.5M +116,414 +179%

ONC Hedge Fund Activity: Q2 2025 in Review

244 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in BeOne Medicines Ltd (ONC) for Q2 2025, worth a combined $8.34B — down 28% from $11.6B a quarter earlier.

Sellers outnumbered buyers: 50 funds closed out of ONC and 28 opened new positions — a net loss of 22 holders — while 83 trimmed existing stakes and 91 added.

The largest buyer was UBS Group, adding an estimated $28.5M. The largest seller was Baillie Gifford & Co, exiting entirely with an estimated $988M sold.

  • 244 institutional investors held BeOne Medicines Ltd (ONC) as of Q2 2025, down from 267 in Q1 2025.
  • Funds reported $8.34B of BeOne Medicines Ltd stock for Q2 2025, down 28% quarter-over-quarter.
  • 28 funds opened new BeOne Medicines Ltd positions in Q2 2025 and 50 closed out, a net change of -22 holders.
  • The largest BeOne Medicines Ltd buyer in Q2 2025 was UBS Group, an estimated $28.5M added.
  • The largest BeOne Medicines Ltd seller in Q2 2025 was Baillie Gifford & Co, an estimated $988M sold.

Based on aggregated 13F filings for Q2 2025.