D.E. Shaw & Co’s Inspire Medical Systems INSP Stock Holding History

D.E. Shaw & Co’s Portfolio INSP Stock Details INSP Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	–	Sell	-11,100	Closed	-$573K	–	5040
2026 Q1	$573K	Buy	+11,100	New	+$777K	﹤0.01%	3782
2025 Q1	–	Sell	-2,500	Closed	-$463K	–	4473
2024 Q4	$463K	Sell	2,500 -47,600	-95%	-$9.24M	﹤0.01%	3665
2024 Q3	$10.6M	Hold	50,100	–	–	0.01%	1396
2024 Q2	$6.7M	Sell	50,100 -10,000	-17%	-$1.89M	0.01%	1625
2024 Q1	$12.9M	Sell	60,100 -10,600	-15%	-$2.08M	0.01%	1208
2023 Q4	$14.4M	Buy	70,700 +33,900	+92%	+$5.49M	0.01%	1131
2023 Q3	$7.3M	Buy	36,800 +7,100	+24%	+$1.79M	0.01%	1501
2023 Q2	$9.64M	Buy	29,700 +9,700	+49%	+$2.77M	0.01%	1367
2023 Q1	$4.68M	Buy	+20,000	New	+$5.06M	0.01%	1990
2022 Q2	–	Sell	-10,000	Closed	-$2.57M	–	5531
2022 Q1	$2.57M	Hold	10,000	–	–	﹤0.01%	3055
2021 Q4	$2.3M	Hold	10,000	–	–	﹤0.01%	3225
2021 Q3	$2.33M	Hold	10,000	–	–	﹤0.01%	2893
2021 Q2	$1.93M	Buy	+10,000	New	+$1.98M	﹤0.01%	2970

Other funds holding INSP

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return

Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM

SCM

Soleus Capital Management Greenwich, Connecticut $2.9B AUM 169.69% 1-Year Est. Return

AQR Capital Management Greenwich, Connecticut $287B AUM 42.33% 1-Year Est. Return

UBS Group Zurich, Switzerland $786B AUM 40.34% 1-Year Est. Return

Nomura Holdings Tokyo, Japan $85.4B AUM 91.09% 1-Year Est. Return

Deerfield Management New York $9.59B AUM 113.36% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

D.E. Shaw & Co's INSP Position: Q2 2026 in Review

D.E. Shaw & Co increased its Inspire Medical Systems (INSP) stake by 24% in Q2 2026, buying an estimated $13.4M and bringing the position to 1,470,462 shares worth $65.6M. The position accounts for 0.03% of the portfolio, ranked #624.

D.E. Shaw & Co first reported a position in INSP in Q3 2018 and has held it in 32 quarters since. The position peaked at $136M in Q2 2023. 276 funds tracked by Wall St. Rank hold INSP as of Q2 2026.

D.E. Shaw & Co held 1,470,462 shares of Inspire Medical Systems worth $65.6M as of Q2 2026.
D.E. Shaw & Co bought 281,925 Inspire Medical Systems shares in Q2 2026, an estimated $13.4M.
Inspire Medical Systems made up 0.03% of D.E. Shaw & Co's portfolio in Q2 2026, its #624 holding.
D.E. Shaw & Co first reported a position in Inspire Medical Systems in Q3 2018 and has held it in 32 quarters since.
D.E. Shaw & Co's Inspire Medical Systems position peaked at $136M in Q2 2023.
276 funds tracked by Wall St. Rank held Inspire Medical Systems as of Q2 2026.

Based on D.E. Shaw & Co's 13F filing for Q2 2026, filed 14 Aug 2026.