D.E. Shaw & Co’s Inspire Medical Systems INSP Stock Holding History

D.E. Shaw & Co’s Portfolio INSP Stock Details INSP Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2024 Q4	–	Sell	-1,300	Closed	-$274K	–	4605
2024 Q3	$274K	Buy	+1,300	New	+$226K	﹤0.01%	4019
2024 Q2	–	Sell	-1,300	Closed	-$279K	–	4646
2024 Q1	$279K	Hold	1,300	–	–	﹤0.01%	3759
2023 Q4	$264K	Buy	+1,300	New	+$211K	﹤0.01%	3791
2022 Q4	–	Sell	-10,600	Closed	-$1.88M	–	4972
2022 Q3	$1.88M	Buy	+10,600	New	+$2.13M	﹤0.01%	3064
2022 Q1	–	Sell	-10,000	Closed	-$2.3M	–	5727
2021 Q4	$2.3M	Buy	+10,000	New	+$2.44M	﹤0.01%	3224
2021 Q2	–	Sell	-10,000	Closed	-$2.07M	–	4868
2021 Q1	$2.07M	Buy	+10,000	New	+$2.13M	﹤0.01%	2553

Other funds holding INSP

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Deerfield Management New York $8.48B AUM 99.04% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

VPM

Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

William Blair Investment Management Chicago, Illinois $30.3B AUM 33.75% 1-Year Est. Return

State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Artisan Partners Milwaukee, Wisconsin $62.3B AUM 26.25% 1-Year Est. Return

Braidwell Stamford, Connecticut $3B AUM 46.72% 1-Year Est. Return

D.E. Shaw & Co's INSP Position: Q1 2026 in Review

D.E. Shaw & Co reduced its Inspire Medical Systems (INSP) stake by 1.9% in Q1 2026, selling an estimated $1.65M and leaving 1,188,537 shares worth $61.3M. The position accounts for 0.04% of the portfolio, ranked #572.

D.E. Shaw & Co first reported a position in INSP in Q3 2018 and has held it in 31 quarters since. The position peaked at $136M in Q2 2023. 301 funds tracked by Wall St. Rank hold INSP as of Q1 2026.

D.E. Shaw & Co held 1,188,537 shares of Inspire Medical Systems worth $61.3M as of Q1 2026.
D.E. Shaw & Co sold 23,625 Inspire Medical Systems shares in Q1 2026, an estimated $1.65M.
Inspire Medical Systems made up 0.04% of D.E. Shaw & Co's portfolio in Q1 2026, its #572 holding.
D.E. Shaw & Co first reported a position in Inspire Medical Systems in Q3 2018 and has held it in 31 quarters since.
D.E. Shaw & Co's Inspire Medical Systems position peaked at $136M in Q2 2023.
301 funds tracked by Wall St. Rank held Inspire Medical Systems as of Q1 2026.

Based on D.E. Shaw & Co's 13F filing for Q1 2026, filed 15 May 2026.