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Cubist Systematic Strategies’s Castle Biosciences CSTL Stock Holding History

Cubist Systematic Strategies’s Portfolio CSTL Stock Details CSTL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		$1.15M Buy
+50,304
New +$1.02M 0.01% 1882
2025
Q2 		– Sell
-237,698
Closed -$4.76M – 3069
2025
Q1 		$4.76M Buy
237,698
+60,161
+34% +$1.49M 0.03% 916
2024
Q4 		$4.73M Sell
177,537
-13,033
-7% -$397K 0.03% 873
2024
Q3 		$5.44M Buy
190,570
+98,095
+106% +$2.5M 0.03% 784
2024
Q2 		$2.01M Buy
92,475
+10,731
+13% +$239K 0.01% 1327
2024
Q1 		$1.81M Buy
81,744
+11,528
+16% +$251K 0.01% 1734
2023
Q4 		$1.52M Sell
70,216
-66,321
-49% -$1.17M 0.01% 1732
2023
Q3 		$2.31M Buy
136,537
+88,647
+185% +$1.55M 0.02% 1272
2023
Q2 		$657K Buy
47,890
+12,773
+36% +$259K ﹤0.01% 2222
2023
Q1 		$798K Buy
35,117
+1,683
+5% +$41.1K ﹤0.01% 2360
2022
Q4 		$787K Sell
33,434
-20,159
-38% -$467K ﹤0.01% 2666
2022
Q3 		$1.4M Sell
53,593
-83,637
-61% -$2.34M 0.01% 2336
2022
Q2 		$3.01M Buy
137,230
+102,397
+294% +$2.38M 0.02% 1452
2022
Q1 		$1.56M Sell
34,833
-4,708
-12% -$195K 0.01% 1688
2021
Q4 		$1.7M Buy
39,541
+32,913
+497% +$1.72M 0.02% 1513
2021
Q3 		$441K Buy
6,628
+904
+16% +$63.6K 0.01% 2121
2021
Q2 		$420K Sell
5,724
-3,377
-37% -$223K ﹤0.01% 2121
2021
Q1 		$623K Buy
9,101
+4,478
+97% +$337K 0.01% 1832
2020
Q4 		$310K Sell
4,623
-13,691
-75% -$742K ﹤0.01% 2013
2020
Q3 		$942K Buy
18,314
+17,723
+2,999% +$788K 0.01% 1371
2020
Q2 		$22K Sell
591
-1,509
-72% -$51.6K ﹤0.01% 2312
2020
Q1 		$63K Buy
+2,100
New +$63.4K ﹤0.01% 1979

Other funds holding CSTL

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return
PCM
Portolan Capital Management Boston, Massachusetts $1.88B AUM 115.74% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return
N
Nuveen Charlotte, North Carolina $369B AUM 31.66% 1-Year Est. Return
B
Braidwell Stamford, Connecticut $3B AUM 46.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
ACM
AIGH Capital Management Baltimore, Maryland $733M AUM 327.32% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Cubist Systematic Strategies's CSTL Position: Q3 2025 in Review

Cubist Systematic Strategies opened a new position in Castle Biosciences (CSTL) in Q3 2025: 50,304 shares worth $1.15M. The stake represents 0.01% of the portfolio and ranks #1882 among its holdings. This is a return to the name: Cubist Systematic Strategies previously reported a position in CSTL as recently as Q1 2025.

Cubist Systematic Strategies first reported a position in CSTL in Q1 2020 and has held it in 22 quarters since. The position peaked at $5.44M in Q3 2024. 173 funds tracked by Wall St. Rank hold CSTL as of Q3 2025.

  • Cubist Systematic Strategies held 50,304 shares of Castle Biosciences worth $1.15M as of Q3 2025.
  • Castle Biosciences was a new Cubist Systematic Strategies position in Q3 2025.
  • Castle Biosciences made up 0.01% of Cubist Systematic Strategies's portfolio in Q3 2025, its #1882 holding.
  • Cubist Systematic Strategies first reported a position in Castle Biosciences in Q1 2020 and has held it in 22 quarters since.
  • Cubist Systematic Strategies's Castle Biosciences position peaked at $5.44M in Q3 2024.
  • 173 funds tracked by Wall St. Rank held Castle Biosciences as of Q3 2025.

Based on Cubist Systematic Strategies's 13F filing for Q3 2025, filed 14 Nov 2025.