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Crestline Management Portfolio holdings

AUM $53.5M
1-Year Est. Return 80.67%
This Fund
S&P 500
This Quarter Est. Return
+6.87%
1 Year Est. Return
+80.67%
3 Year Est. Return
+80.2%
5 Year Est. Return
+49.87%
10 Year Est. Return
+446.13%
AUM
$58.1M
AUM Growth
-$4.47M
Cap. Flow
-$8.64M
Cap. Flow %
-14.87%
Top 10 Hldgs %
100%
Holding
3
New
–
Increased
–
Reduced
2
Closed
–

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
DNLI icon
Denali Therapeutics
DNLI
+$6.47M
2
SANA icon
Sana Biotechnology
SANA
+$2.17M

Sector Composition

Rank Sector Weight
1 Healthcare 96.38%
2 Technology 3.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DNLI icon
1
Denali Therapeutics
DNLI
$3.84B
$49.5M 85.26%
3,410,732
-450,000
-12% -$6.47M
SANA icon
2
Sana Biotechnology
SANA
$1.18B
$6.46M 11.13%
1,820,937
-600,000
-25% -$2.17M
EGHT icon
3
8x8 Inc
EGHT
$287M
$2.1M 3.62%
990,580
– –

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Crestline Management's Q3 2025 Portfolio in Review

As of Q3 2025, Crestline Management held 3 positions worth $58.1M, down 7.2% from $62.6M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Crestline Management withdrew a net $8.64M in Q3 2025, reducing 2 holdings. Its largest reduction was Denali Therapeutics, cutting an estimated $6.47M.

By sector, the portfolio is most concentrated in Healthcare at 96% of assets, down from 97% a quarter earlier, followed by Technology.

  • Crestline Management's biggest Q3 2025 reduction was Denali Therapeutics, cutting an estimated $6.47M.
  • Crestline Management's ten largest holdings make up 100% of its $58.1M portfolio in Q3 2025.
  • Crestline Management opened 0 new positions and closed 0 in Q3 2025.
  • Crestline Management's portfolio value fell 7.2% quarter-over-quarter to $58.1M.

Based on Crestline Management's 13F filing for Q3 2025, filed 14 Nov 2025.