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B

Braidwell Portfolio holdings

AUM $2.7B
1-Year Est. Return 88.53%
This Fund
S&P 500
This Quarter Est. Return
+31.47%
1 Year Est. Return
+88.53%
3 Year Est. Return
+96.53%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$2.7B
AUM Growth
-$294M
Cap. Flow
-$772M
Cap. Flow %
-28.57%
Top 10 Hldgs %
31.56%
Holding
109
New
24
Increased
20
Reduced
34
Closed
23
Avg Time Held
3.5 quarters
Top 10 Avg Time Held
1.6 quarters
Top 20 Avg Time Held
2.5 quarters

Sector Composition

Rank Sector Weight
1 Healthcare 95.44%
2 Miscellaneous 3.68%
3 Financials 0.88%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
CAI icon
1
Caris Life Sciences
CAI
$8.35B
$147M 5.44%
8,256,032
+246,585
+3% +$4.41M
2025 Q2
4 quarters
HNGE icon
2
Hinge Health
HNGE
$8.48B
$110M 4.08%
1,330,127
-124,996
-9% -$6.79M
2025 Q3
3 quarters
GKOS icon
3
Glaukos
GKOS
$9.76B
$82.7M 3.06%
591,927
-171,578
-22% -$21.7M
2022 Q4
14 quarters
EWTX icon
4
Edgewise Therapeutics
EWTX
$3.94B
$81.1M 3%
1,996,965
-350,618
-15% -$12.1M
2024 Q3
7 quarters
SYRE icon
5
Spyre Therapeutics
SYRE
$7.52B
$78.1M 2.89%
879,467
-53,356
-6% -$3.89M
2023 Q4
10 quarters
IRTC icon
6
iRhythm Holdings
IRTC
$3.55B
$77.8M 2.88%
654,262
+44,070
+7% +$5.12M
2022 Q4
14 quarters
NEO icon
7
NeoGenomics
NEO
$2.14B
$71.8M 2.65%
4,918,202
-699,200
-12% -$6.75M
2025 Q3
3 quarters
KOD icon
8
Kodiak Sciences
KOD
$5.76B
$69.6M 2.58%
1,787,318
-31,347
-2% -$1.22M
2025 Q4
2 quarters
XENE icon
9
Xenon Pharmaceuticals
XENE
$3.33B
$68.3M 2.53%
1,131,452
-207,000
-15% -$11.5M
2022 Q4
14 quarters
GLUE icon
10
Monte Rosa Therapeutics
GLUE
$844M
$59.3M 2.19%
2,451,562
-755,012
-24% -$14.3M
2025 Q4
2 quarters
DNTH icon
11
Dianthus Therapeutics
DNTH
$4.34B
$58M 2.14%
594,562
-304,802
-34% -$26.6M
2025 Q3
3 quarters
NBIX icon
12
Neurocrine Biosciences
NBIX
$13.7B
$56.7M 2.1%
336,171
-315,950
-48% -$46.9M
2023 Q1
13 quarters
ATEC icon
13
Alphatec Holdings
ATEC
$1.67B
$56.5M 2.09%
6,531,439
+4,358,714
+201% +$39.7M
2026 Q1
1 quarter
GENB icon
14
Generate Biomedicines
GENB
$1.57B
$55.4M 2.05%
3,283,844
-309,155
-9% -$4.21M
2026 Q1
1 quarter
MRVI icon
15
Maravai LifeSciences
MRVI
$973M
$54.3M 2.01%
8,702,921
-1,537,243
-15% -$6.64M
2023 Q2
12 quarters
KRYS icon
16
Krystal Biotech
KRYS
$9.51B
$47.9M 1.77%
128,975
-53,450
-29% -$16M
2022 Q4
14 quarters
HUM icon
17
Humana
HUM
$50.5B
$45.5M 1.68%
+114,500
New +$32.6M
2026 Q2
0 quarters
TMO icon
18
Thermo Fisher Scientific
TMO
$245B
$44.8M 1.66%
89,395
-3,520
-4% -$1.69M
2024 Q4
6 quarters
KYMR icon
19
Kymera Therapeutics
KYMR
$8.87B
$43.4M 1.6%
378,163
+40,604
+12% +$3.49M
2025 Q3
3 quarters
RYTM icon
20
Rhythm Pharmaceuticals
RYTM
$5.96B
$42.3M 1.57%
381,128
+70,500
+23% +$6.37M
2026 Q1
1 quarter
DMRA
21
Damora Therapeutics
DMRA
$1.15B
$42.1M 1.56%
1,620,377
+725,531
+81% +$17.6M
2026 Q1
1 quarter
ACAD icon
22
Acadia Pharmaceuticals
ACAD
$3.21B
$41.7M 1.54%
1,646,399
-824,800
-33% -$18.1M
2025 Q3
3 quarters
BTSG icon
23
BrightSpring Health Services
BTSG
$12.4B
$41.6M 1.54%
596,753
-419,809
-41% -$23.3M
2025 Q4
2 quarters
TMDX icon
24
Transmedics
TMDX
$2.74B
$40.5M 1.5%
609,715
+280,324
+85% +$23.7M
2024 Q4
6 quarters
MBX icon
25
MBX Biosciences
MBX
$2.36B
$39.2M 1.45%
710,880
-781,587
-52% -$27.3M
2025 Q4
2 quarters

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Braidwell's Q2 2026 Portfolio in Review

As of Q2 2026, Braidwell held 109 positions worth $2.7B, down 9.8% from $3B the previous quarter. Its ten largest holdings account for 32% of the portfolio.

Braidwell withdrew a net $772M in Q2 2026, closing 23 positions and reducing 34 holdings. Its most notable exit was Centessa Pharmaceuticals, an estimated $78.9M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 95% of assets, up from 87% a quarter earlier, followed by Miscellaneous and Financials.

Against the trend, Braidwell opened a new position in Humana worth $45.5M.

  • Braidwell's largest Q2 2026 buy was Humana: 114,500 shares worth $45.5M.
  • Braidwell added most to Alphatec Holdings in Q2 2026, an estimated $39.7M increase.
  • Braidwell's biggest Q2 2026 reduction was argenx, cutting an estimated $55.5M.
  • Braidwell fully exited Centessa Pharmaceuticals in Q2 2026, selling an estimated $78.9M.
  • Braidwell's ten largest holdings make up 32% of its $2.7B portfolio in Q2 2026.
  • Braidwell opened 24 new positions and closed 23 in Q2 2026.
  • Braidwell's portfolio value fell 9.8% quarter-over-quarter to $2.7B.

Based on Braidwell's 13F filing for Q2 2026, filed 14 Aug 2026.