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AVM

Arch Venture Management Portfolio holdings

AUM $677M
1-Year Est. Return 322.07%
This Fund
S&P 500
This Quarter Est. Return
+5.62%
1 Year Est. Return
+322.07%
3 Year Est. Return
+208.96%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$299M
AUM Growth
+$92.9M
Cap. Flow
+$86.1M
Cap. Flow %
28.79%
Top 10 Hldgs %
99.93%
Holding
11
New
2
Increased
1
Reduced
–
Closed
–

Top Buys

Rank Stock Value
1
VIR icon
Vir Biotechnology
VIR
+$69.3M
2
LYEL icon
Lyell Immunopharma
LYEL
+$16.6M
3
CERO
CERo Therapeutics
CERO
+$265K

Top Sells

No sells this quarter

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BEAM icon
1
Beam Therapeutics
BEAM
$2.73B
$77.2M 25.82%
4,540,132
– –
VIR icon
2
Vir Biotechnology
VIR
$1.5B
$65.1M 21.76%
+12,916,663
New +$69.3M
MAZE
3
Maze Therapeutics
MAZE
$1.53B
$50.6M 16.91%
4,120,053
– –
RAPP
4
Rapport Therapeutics
RAPP
$2.05B
$42.4M 14.19%
3,728,738
– –
VERV
5
DELISTED
Verve Therapeutics
VERV
$22.6M 7.54%
2,008,809
– –
LYEL icon
6
Lyell Immunopharma
LYEL
$336M
$16.1M 5.39%
+1,820,634
New +$16.6M
ERAS icon
7
Erasca
ERAS
$6.48B
$14.1M 4.71%
11,055,554
– –
GOSS icon
8
Gossamer Bio
GOSS
$87.2M
$9.91M 3.31%
8,055,916
– –
QTTB icon
9
Q32 Bio
QTTB
$462M
$478K 0.16%
320,482
– –
UBX
10
DELISTED
Unity Biotechnology
UBX
$386K 0.13%
1,004,817
– –
CERO
11
DELISTED
CERo Therapeutics
CERO
$216K 0.07%
22,389
+21,284
+1,926% +$265K

Similar funds

NI
Noked Israel Ramat Hasharon, Israel $677M AUM 69.37% 1-Year Est. Return
MMPW
Mitchell McLeod Pugh & Williams Mobile, Alabama $678M AUM 23.02% 1-Year Est. Return
JC
JBF Capital Aspen, Colorado $676M AUM 24.74% 1-Year Est. Return
NCM
Noesis Capital Mangement Boca Raton, Florida $676M AUM 34.17% 1-Year Est. Return
TWM
Topsail Wealth Management Charlotte, North Carolina $678M AUM 13.87% 1-Year Est. Return
DLIC
Daido Life Insurance Company Osaka, Japan $678M AUM 16.09% 1-Year Est. Return
REAM
Ripple Effect Asset Management New York $679M AUM 81.6% 1-Year Est. Return
MCO
MAK Capital One New York $679M AUM 29.02% 1-Year Est. Return

Arch Venture Management's Q2 2025 Portfolio in Review

As of Q2 2025, Arch Venture Management held 11 positions worth $299M, up 45% from $206M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Arch Venture Management deployed $86.1M of net new capital in Q2 2025, opening 2 new positions and adding to 1 existing holding. Its largest new stake was Vir Biotechnology: 12,916,663 shares worth $65.1M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, unchanged from a quarter earlier.

  • Arch Venture Management's largest Q2 2025 buy was Vir Biotechnology: 12,916,663 shares worth $65.1M.
  • Arch Venture Management added most to CERo Therapeutics in Q2 2025, an estimated $265K increase.
  • Arch Venture Management's ten largest holdings make up 100% of its $299M portfolio in Q2 2025.
  • Arch Venture Management opened 2 new positions and closed 0 in Q2 2025.
  • Arch Venture Management's portfolio value rose 45% quarter-over-quarter to $299M.

Based on Arch Venture Management's 13F filing for Q2 2025, filed 14 Aug 2025.