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AVM

Arch Venture Management Portfolio holdings

AUM $677M
1-Year Est. Return 322.07%
This Fund
S&P 500
This Quarter Est. Return
-27.67%
1 Year Est. Return
+322.07%
3 Year Est. Return
+208.96%
5 Year Est. Return
–
10 Year Est. Return
–
AUM
$390M
AUM Growth
-$381M
Cap. Flow
-$185M
Cap. Flow %
-47.4%
Top 10 Hldgs %
100%
Holding
10
New
–
Increased
–
Reduced
2
Closed
2

Top Buys

No buys this quarter

Top Sells

Rank Stock Value
1
KRTX
Karuna Therapeutics, Inc. Common Stock
KRTX
+$172M
2
REVH
Revolution Healthcare Acquisition Corp. SAIL Class A Common Stock
REVH
+$13.3M
3
RUBY
Rubius Therapeutics, Inc
RUBY
+$152K
4
UBX
Unity Biotechnology
UBX
+$3

Sector Composition

Rank Sector Weight
1 Healthcare 100%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DNLI icon
1
Denali Therapeutics
DNLI
$3.7B
$102M 26.13%
3,668,749
– –
KRTX
2
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
$101M 25.81%
512,872
-800,000
-61% -$172M
EQRX
3
DELISTED
EQRx, Inc. Common Stock
EQRX
$89.4M 22.89%
36,335,375
– –
ERAS icon
4
Erasca
ERAS
$6.66B
$47.6M 12.2%
11,055,554
– –
VERV
5
DELISTED
Verve Therapeutics
VERV
$38.9M 9.96%
2,008,809
– –
OMIC
6
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$7.64M 1.96%
126,631
– –
UBX
7
DELISTED
Unity Biotechnology
UBX
$2.75M 0.71%
1,004,817
-1
-0% -$3
MTCR
8
DELISTED
Metacrine, Inc. Common Stock
MTCR
$1.32M 0.34%
2,940,503
– –
RUBY
9
DELISTED
Rubius Therapeutics, Inc
RUBY
– –
-349,908
Closed -$152K
REVH
10
DELISTED
Revolution Healthcare Acquisition Corp. SAIL Class A Common Stock
REVH
– –
-1,357,237
Closed -$13.3M

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JC
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Arch Venture Management's Q4 2022 Portfolio in Review

As of Q4 2022, Arch Venture Management held 10 positions worth $390M, down 49% from $771M the previous quarter. Its ten largest holdings account for 100% of the portfolio.

Arch Venture Management withdrew a net $185M in Q4 2022, closing 2 positions and reducing 2 holdings. Its most notable exit was Revolution Healthcare Acquisition Corp. SAIL Class A Common Stock, an estimated $13.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 98% a quarter earlier, followed by Financials.

  • Arch Venture Management's biggest Q4 2022 reduction was Karuna Therapeutics, Inc. Common Stock, cutting an estimated $172M.
  • Arch Venture Management fully exited Revolution Healthcare Acquisition Corp. SAIL Class A Common Stock in Q4 2022, selling an estimated $13.3M.
  • Arch Venture Management's ten largest holdings make up 100% of its $390M portfolio in Q4 2022.
  • Arch Venture Management opened 0 new positions and closed 2 in Q4 2022.
  • Arch Venture Management's portfolio value fell 49% quarter-over-quarter to $390M.

Based on Arch Venture Management's 13F filing for Q4 2022, filed 14 Feb 2023.