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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ABVX
176
Abivax
ABVX
$10.9B
$74.2M 0.11%
550,000
-427,629
-44% -$46.7M
LMT icon
177
Lockheed Martin
LMT
$136B
$74M 0.11%
152,993
-33,800
-18% -$16.2M
ALGM icon
178
Allegro MicroSystems
ALGM
$7.99B
$74M 0.11%
2,803,944
+1,227,317
+78% +$33.8M
BNY
179
Bank of New York Mellon
BNY
$106B
$73.1M 0.11%
629,516
-11,800
-2% -$1.31M
MDLZ icon
180
Mondelez International
MDLZ
$79.2B
$72.9M 0.11%
1,354,197
+365,500
+37% +$21M
PEG icon
181
Public Service Enterprise Group
PEG
$38B
$72.9M 0.11%
907,750
+653,366
+257% +$53.3M
ELV icon
182
Elevance Health
ELV
$82B
$71.7M 0.11%
204,593
+33,145
+19% +$11.2M
PCAR icon
183
PACCAR
PCAR
$71.6B
$71.1M 0.11%
649,198
+251,200
+63% +$25.7M
MPWR icon
184
Monolithic Power Systems
MPWR
$65.6B
$70.6M 0.11%
77,852
-5,300
-6% -$5.1M
CME icon
185
CME Group
CME
$94.4B
$70.4M 0.11%
257,754
+8,523
+3% +$2.32M
CYBR
186
DELISTED
CyberArk
CYBR
$69.6M 0.11%
156,078
-131,154
-46% -$63.1M
MCO icon
187
Moody's
MCO
$83.8B
$68.8M 0.1%
134,754
-1,500
-1% -$732K
GM icon
188
General Motors
GM
$77.5B
$68.5M 0.1%
842,186
+251,400
+43% +$17.7M
NBR icon
189
Nabors Industries
NBR
$1.24B
$68.4M 0.1%
1,260,000
+485,000
+63% +$23.6M
AIT icon
190
Applied Industrial Technologies
AIT
$13.2B
$67.9M 0.1%
264,575
+259,319
+4,934% +$66.3M
TDG icon
191
TransDigm Group
TDG
$71.3B
$67.8M 0.1%
50,994
+2,099
+4% +$2.75M
CDNS icon
192
Cadence Design Systems
CDNS
$93.8B
$67.4M 0.1%
215,745
+12,900
+6% +$4.21M
AXSM icon
193
Axsome Therapeutics
AXSM
$10.9B
$67.1M 0.1%
367,578
-77,422
-17% -$10.8M
ED icon
194
Consolidated Edison
ED
$40B
$67.1M 0.1%
+675,844
New +$67.1M
ASML icon
195
ASML
ASML
$658B
$66.9M 0.1%
62,500
-2,500
-4% -$2.61M
RYTM icon
196
Rhythm Pharmaceuticals
RYTM
$7.26B
$66.5M 0.1%
621,585
+77,585
+14% +$8.23M
TEL icon
197
TE Connectivity
TEL
$62.9B
$66.2M 0.1%
290,844
+22,100
+8% +$5.11M
FCX icon
198
Freeport-McMoran
FCX
$96.7B
$65.8M 0.1%
1,296,400
-10,700
-0.8% -$464K
USB icon
199
US Bancorp
USB
$100B
$65.7M 0.1%
1,231,330
-178,770
-13% -$8.79M
COR icon
200
Cencora
COR
$59.6B
$65.4M 0.1%
193,500
+17,200
+10% +$5.86M
6 7
8
9 10

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.