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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
MO icon
151
Altria Group
MO
$113B
$87.5M 0.13%
1,517,232
-10,400
-0.7% -$628K
CNR
152
Core Natural Resources Inc
CNR
$4.08B
$86.3M 0.13%
+975,000
New +$83.1M
EYPT icon
153
EyePoint Inc
EYPT
$989M
$85.9M 0.13%
4,700,000
-859,782
-15% -$12.2M
MAR icon
154
Marriott International
MAR
$89.9B
$85.1M 0.13%
274,325
-82,400
-23% -$23.5M
NEM icon
155
Newmont
NEM
$104B
$84.5M 0.13%
846,300
-152,600
-15% -$13.8M
DE icon
156
Deere & Co
DE
$167B
$84.3M 0.13%
181,114
-72,650
-29% -$34.1M
HON icon
157
Honeywell
HON
$79B
$83.6M 0.13%
428,417
-139,659
-25% -$27.3M
ICE icon
158
Intercontinental Exchange
ICE
$83.7B
$83.4M 0.13%
514,759
-55,800
-10% -$8.74M
RYAN icon
159
Ryan Specialty Holdings
RYAN
$5.68B
$83.1M 0.13%
1,610,000
+1,510,000
+1,510% +$82.8M
SBUX icon
160
Starbucks
SBUX
$120B
$82.7M 0.13%
982,509
-51,200
-5% -$4.32M
PLD icon
161
Prologis
PLD
$131B
$82.3M 0.12%
644,529
-9,400
-1% -$1.17M
SLAB icon
162
Silicon Laboratories
SLAB
$7.19B
$80.6M 0.12%
616,475
+151,664
+33% +$19.9M
HWM icon
163
Howmet Aerospace
HWM
$116B
$80.6M 0.12%
393,000
-53,600
-12% -$10.7M
HOOD icon
164
Robinhood
HOOD
$83.7B
$80.3M 0.12%
709,900
+6,100
+0.9% +$793K
TMUS icon
165
T-Mobile US
TMUS
$189B
$80.1M 0.12%
394,734
-30,300
-7% -$6.42M
PCVX icon
166
Vaxcyte
PCVX
$7.93B
$79.6M 0.12%
1,725,000
+1,392,000
+418% +$62.3M
KKR icon
167
KKR & Co
KKR
$96.5B
$79.1M 0.12%
620,400
-56,500
-8% -$7.03M
SNPS icon
168
Synopsys
SNPS
$76.9B
$79M 0.12%
168,144
-15,900
-9% -$7.06M
NKE icon
169
Nike
NKE
$62B
$78.7M 0.12%
1,234,961
-95,400
-7% -$6.22M
HOLX
170
DELISTED
Hologic
HOLX
$78.3M 0.12%
1,051,259
+766,170
+269% +$56M
AYI icon
171
Acuity Brands
AYI
$10.4B
$78.2M 0.12%
+217,335
New +$78.6M
KVUE icon
172
Kenvue
KVUE
$37.3B
$78.1M 0.12%
4,529,558
+2,282,500
+102% +$37.3M
POOL icon
173
Pool Corp
POOL
$7.35B
$77.7M 0.12%
339,716
+243,907
+255% +$63.4M
DASH icon
174
DoorDash
DASH
$87.5B
$76.4M 0.12%
337,500
+75,900
+29% +$17.8M
AMT icon
175
American Tower
AMT
$81.6B
$74.2M 0.11%
422,605
-3,200
-0.8% -$582K
5 6
7
8 9

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.