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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
BX icon
126
Blackstone
BX
$110B
$101M 0.15%
656,700
+4,400
+0.7% +$669K
DYN icon
127
Dyne Therapeutics
DYN
$4.85B
$101M 0.15%
5,172,000
+1,618,000
+46% +$30.6M
ETN icon
128
Eaton
ETN
$173B
$100M 0.15%
315,070
-2,058
-0.6% -$729K
CEG icon
129
Constellation Energy
CEG
$95.4B
$99.6M 0.15%
281,977
-37,100
-12% -$13.5M
JBTM
130
JBT Marel
JBTM
$6.9B
$99.5M 0.15%
660,361
+48,222
+8% +$6.8M
CRWD icon
131
CrowdStrike
CRWD
$215B
$97.3M 0.15%
830,400
-400
-0% -$50.9K
UNM icon
132
Unum
UNM
$14.5B
$96.9M 0.15%
1,250,000
+50,000
+4% +$3.82M
IDYA icon
133
IDEAYA Biosciences
IDYA
$3.48B
$96.8M 0.15%
2,800,000
-100,094
-3% -$3.19M
PGR icon
134
Progressive
PGR
$123B
$96.8M 0.15%
424,985
-43,100
-9% -$9.73M
PSX icon
135
Phillips 66
PSX
$82.5B
$95.3M 0.14%
738,801
+345,900
+88% +$46.6M
TRV icon
136
Travelers Companies
TRV
$78.7B
$95.1M 0.14%
328,004
-34,500
-10% -$9.71M
TNGX icon
137
Tango Therapeutics
TNGX
$4.78B
$94M 0.14%
10,607,924
+8,096,924
+322% +$69.8M
LBRDK icon
138
Liberty Broadband Class C
LBRDK
$5.17B
$93.5M 0.14%
1,923,945
-614,322
-24% -$31.9M
JAZZ icon
139
Jazz Pharmaceuticals
JAZZ
$16.4B
$93.2M 0.14%
548,000
+395,000
+258% +$60.6M
SR icon
140
Spire
SR
$4.7B
$92.9M 0.14%
1,123,220
+462,500
+70% +$39.4M
GPOR icon
141
Gulfport Energy Corp
GPOR
$2.8B
$92.8M 0.14%
446,227
-13,011
-3% -$2.59M
HESM icon
142
Hess Midstream
HESM
$5.17B
$92.3M 0.14%
+2,675,000
New +$89.9M
CMCSA icon
143
Comcast
CMCSA
$88.5B
$92.1M 0.14%
3,081,159
+57,200
+2% +$1.63M
CVE icon
144
Cenovus Energy
CVE
$53B
$90.8M 0.14%
5,368,262
+875,000
+19% +$15.2M
MCK icon
145
McKesson
MCK
$97.2B
$90.8M 0.14%
110,660
+21,262
+24% +$17.4M
WELL icon
146
Welltower
WELL
$167B
$90.1M 0.14%
485,306
-122,900
-20% -$23M
AMGN icon
147
Amgen
AMGN
$210B
$89.8M 0.14%
274,292
+36,600
+15% +$11.6M
GD icon
148
General Dynamics
GD
$104B
$88.8M 0.13%
263,910
-95,305
-27% -$32.5M
CBRE icon
149
CBRE Group
CBRE
$43.7B
$88.4M 0.13%
549,600
+82,800
+18% +$13M
EVRG icon
150
Evergy
EVRG
$19.3B
$87.6M 0.13%
1,207,882
+998,400
+477% +$75.7M
4 5
6
7 8

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.