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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
VRTX icon
101
Vertex Pharmaceuticals
VRTX
$121B
$124M 0.19%
272,474
-210,021
-44% -$90.5M
ADBE icon
102
Adobe
ADBE
$101B
$124M 0.19%
352,878
-12,900
-4% -$4.39M
TJX icon
103
TJX Companies
TJX
$174B
$123M 0.19%
802,548
-17,900
-2% -$2.65M
MDT icon
104
Medtronic
MDT
$110B
$122M 0.19%
1,273,871
-906,646
-42% -$88.1M
TXN icon
105
Texas Instruments
TXN
$258B
$122M 0.18%
704,244
-49,900
-7% -$8.55M
CI icon
106
Cigna
CI
$72.3B
$121M 0.18%
438,151
+264,549
+152% +$74.2M
SDRL icon
107
Seadrill
SDRL
$2.61B
$121M 0.18%
3,484,940
+373,176
+12% +$11.6M
ANET icon
108
Arista Networks
ANET
$243B
$120M 0.18%
917,200
+20,000
+2% +$2.75M
BLK icon
109
Blackrock
BLK
$176B
$119M 0.18%
111,464
-9,516
-8% -$10.4M
AR icon
110
Antero Resources
AR
$10.9B
$118M 0.18%
3,438,110
+415,000
+14% +$14.1M
CHRD icon
111
Chord Energy
CHRD
$7.71B
$115M 0.17%
1,243,850
+193,469
+18% +$17.9M
LOW icon
112
Lowe's Companies
LOW
$122B
$114M 0.17%
472,905
-90,200
-16% -$21.7M
CB icon
113
Chubb
CB
$134B
$114M 0.17%
364,883
-46,800
-11% -$13.7M
WBD icon
114
Warner Bros
WBD
$65.2B
$113M 0.17%
3,923,383
+1,669,540
+74% +$39M
TVTX icon
115
Travere Therapeutics
TVTX
$5.1B
$112M 0.17%
2,927,000
-625,000
-18% -$20.3M
BKH icon
116
Black Hills Corp
BKH
$5.47B
$111M 0.17%
1,592,000
+1,017,000
+177% +$68.6M
CRH icon
117
CRH
CRH
$66B
$110M 0.17%
880,100
+427,100
+94% +$50.9M
EXAS
118
DELISTED
Exact Sciences
EXAS
$108M 0.16%
+1,067,342
New +$85.7M
EA icon
119
Electronic Arts
EA
$53B
$107M 0.16%
526,018
+196,052
+59% +$39.6M
CMI icon
120
Cummins
CMI
$86.4B
$107M 0.16%
209,666
+108,400
+107% +$50.7M
DXCM icon
121
DexCom
DXCM
$32.8B
$105M 0.16%
1,587,550
+1,380,550
+667% +$89.3M
ADI icon
122
Analog Devices
ADI
$184B
$103M 0.16%
381,414
+10,900
+3% +$2.74M
GILD icon
123
Gilead Sciences
GILD
$162B
$103M 0.16%
841,165
-514,083
-38% -$62.5M
NEE icon
124
NextEra Energy
NEE
$180B
$103M 0.16%
1,284,129
-1,288,484
-50% -$107M
VTR icon
125
Ventas
VTR
$46B
$103M 0.16%
1,326,026
-393,674
-23% -$29.7M
3 4
5
6 7

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.