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Adage Capital Partners Portfolio holdings
AUM
$64.8B
1-Year Est. Return
42.7%
This Fund
S&P 500
This Quarter
Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
(+4.7%)
Cap. Flow
+$25.6M
Cap. Flow
% of AUM
0.04%
Top 10 Holdings %
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Merck
MRK
|
+$153M |
| 2 |
Boeing
BA
|
+$150M |
| 3 |
Dominion Energy
D
|
+$129M |
| 4 |
ConocoPhillips
COP
|
+$99.9M |
| 5 |
Revolution Medicines
RVMD
|
+$95.9M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Praxis Precision Medicines
PRAX
|
+$262M |
| 2 |
Chevron
CVX
|
+$229M |
| 3 |
Insmed
INSM
|
+$174M |
| 4 |
Procter & Gamble
PG
|
+$142M |
| 5 |
ETNB
89bio
ETNB
|
+$134M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 29.21% |
| 2 | Healthcare | 15.27% |
| 3 | Financials | 12.11% |
| 4 | Communication Services | 9.26% |
| 5 | Consumer Discretionary | 9.03% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
HTO
1001
H2O America
HTO
$2.58B
| – | – |
-100,000
| Closed | -$4.87M |
|
1002
Silgan Holdings
SLGN
$4.43B
| – | – |
-284,526
| Closed | -$12.2M |
|
|
SLNO
1003
DELISTED
Soleno Therapeutics
SLNO
| – | – |
-1,401,576
| Closed | -$94.7M |
|
1004
iShares Silver Trust
SLV
$29.7B
| – | – |
-150,000
| Closed | -$6.36M |
|
1005
Syndax Pharmaceuticals
SNDX
$1.75B
| – | – |
-3,311,963
| Closed | -$51M |
|
1006
Southern Company
SO
$107B
| – | – |
-300,300
| Closed | -$28.5M |
|
1007
Invesco S&P 500 Low Volatility ETF
SPLV
$7.22B
| – | – |
-180,000
| Closed | -$13.2M |
|
|
SPR
1008
DELISTED
Spirit AeroSystems
SPR
| – | – |
-1,440,641
| Closed | -$55.6M |
|
|
SRDX
1009
DELISTED
Surmodics
SRDX
| – | – |
-91,270
| Closed | -$2.73M |
|
1010
Scholar Rock
SRRK
$6.37B
| – | – |
-1,951,866
| Closed | -$72.7M |
|
1011
Skyworks Solutions
SWKS
$10.1B
| – | – |
-135,150
| Closed | -$10.4M |
|
1012
Stock Yards Bancorp
SYBT
$2.6B
| – | – |
-87,500
| Closed | -$6.12M |
|
1013
TTM Technologies
TTMI
$14.7B
| – | – |
-654,174
| Closed | -$37.7M |
|
1014
US Physical Therapy
USPH
$1.16B
| – | – |
-32,000
| Closed | -$2.72M |
|
1015
Vale
VALE
$62.9B
| – | – |
-1,400,000
| Closed | -$15.2M |
|
1016
Visteon
VC
$2.78B
| – | – |
-175,000
| Closed | -$21M |
|
1017
Veru
VERU
$37.4M
| – | – |
-100,000
| Closed | -$380K |
|
1018
Vista Energy
VIST
$7.28B
| – | – |
-125,000
| Closed | -$4.3M |
|
1019
Voya Financial
VOYA
$9.13B
| – | – |
-325,000
| Closed | -$24.3M |
|
1020
Vestis
VSTS
$1.83B
| – | – |
-444,844
| Closed | -$2.02M |
|
1021
Viatris
VTRS
$19.9B
| – | – |
-367,136
| Closed | -$3.63M |
|
1022
Valvoline
VVV
$4.56B
| – | – |
-250,000
| Closed | -$8.98M |
|
|
WCN
1023
Waste Connections
WCN
$42B
| – | – |
-46,696
| Closed | -$8.21M |
|
1024
WEC Energy
WEC
$35.2B
| – | – |
-293,008
| Closed | -$33.6M |
|
1025
Dentsply Sirona
XRAY
$2.67B
| – | – |
-397,775
| Closed | -$5.05M |
|
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Adage Capital Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.
Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.
By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.
- Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
- Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
- Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
- Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
- Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
- Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
- Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.
Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.