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Adage Capital Partners Portfolio holdings
AUM
$64.8B
1-Year Est. Return
42.7%
This Fund
S&P 500
This Quarter
Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
(+4.7%)
Cap. Flow
+$25.6M
Cap. Flow
% of AUM
0.04%
Top 10 Holdings %
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Merck
MRK
|
+$153M |
| 2 |
Boeing
BA
|
+$150M |
| 3 |
Dominion Energy
D
|
+$129M |
| 4 |
ConocoPhillips
COP
|
+$99.9M |
| 5 |
Revolution Medicines
RVMD
|
+$95.9M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Praxis Precision Medicines
PRAX
|
+$262M |
| 2 |
Chevron
CVX
|
+$229M |
| 3 |
Insmed
INSM
|
+$174M |
| 4 |
Procter & Gamble
PG
|
+$142M |
| 5 |
ETNB
89bio
ETNB
|
+$134M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 29.21% |
| 2 | Healthcare | 15.27% |
| 3 | Financials | 12.11% |
| 4 | Communication Services | 9.26% |
| 5 | Consumer Discretionary | 9.03% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
976
M&T Bank
MTB
$36.2B
| – | – |
-62,307
| Closed | -$12.3M |
|
977
NextDecade
NEXT
$1.77B
| – | – |
-300,000
| Closed | -$2.04M |
|
978
Owens Corning
OC
$12.3B
| – | – |
-10,000
| Closed | -$1.41M |
|
979
Oshkosh
OSK
$9.48B
| – | – |
-67,000
| Closed | -$8.69M |
|
|
PCH
980
DELISTED
PotlatchDeltic
PCH
| – | – |
-30,000
| Closed | -$1.22M |
|
981
Pacira BioSciences
PCRX
$999M
| – | – |
-409,997
| Closed | -$10.6M |
|
|
PLYM
982
DELISTED
Plymouth Industrial REIT
PLYM
| – | – |
-734,500
| Closed | -$16.4M |
|
983
Pennant Group
PNTG
$1.34B
| – | – |
-139,613
| Closed | -$3.52M |
|
984
Primoris Services
PRIM
$4.55B
| – | – |
-175,000
| Closed | -$24M |
|
985
Prime Medicine
PRME
$560M
| – | – |
-771,361
| Closed | -$4.27M |
|
986
Public Storage
PSA
$61.1B
| – | – |
-8,792
| Closed | -$2.54M |
|
987
Patterson-UTI
PTEN
$3.8B
| – | – |
-60,000
| Closed | -$311K |
|
988
Arcus Biosciences
RCUS
$3.6B
| – | – |
-152,000
| Closed | -$2.07M |
|
989
Rexford Industrial Realty
REXR
$8.25B
| – | – |
-50,000
| Closed | -$2.06M |
|
990
Repligen
RGEN
$9.09B
| – | – |
-5,000
| Closed | -$668K |
|
991
Reinsurance Group of America
RGA
$15.5B
| – | – |
-250,000
| Closed | -$48M |
|
992
ResMed
RMD
$32.6B
| – | – |
-42,531
| Closed | -$11.6M |
|
993
Renasant Corp
RNST
$4.01B
| – | – |
-334,836
| Closed | -$12.4M |
|
994
Rollins
ROL
$17.8B
| – | – |
-189,342
| Closed | -$11.1M |
|
995
Republic Services
RSG
$63.5B
| – | – |
-183,968
| Closed | -$42.2M |
|
996
Revvity
RVTY
$12.6B
| – | – |
-105,688
| Closed | -$9.26M |
|
997
Saic
SAIC
$5.19B
| – | – |
-15,000
| Closed | -$1.49M |
|
998
Service Corp International
SCI
$11.5B
| – | – |
-110,603
| Closed | -$9.2M |
|
999
Simmons First National
SFNC
$3.45B
| – | – |
-199,734
| Closed | -$3.83M |
|
1000
SiteOne Landscape Supply
SITE
$4.39B
| – | – |
-8,773
| Closed | -$1.13M |
|
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Adage Capital Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.
Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.
By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.
- Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
- Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
- Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
- Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
- Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
- Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
- Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.
Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.