Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $54B

AUM

$54B

AUM Growth

-$3.22B (-6%)

Cap. Flow

+$807M

Cap. Flow % of AUM

1.5%

Top 10 Holdings %Top 10 Hldgs %

28.72%

Holding

985

New

115

Increased

314

Reduced

359

Closed

149

Top Buys

1	Hubbell HUBB	$208M
2	Norfolk Southern NSC	$145M
3	Insmed INSM	$137M
4	Vertex Pharmaceuticals VRTX	$136M
5	Soleno Therapeutics SLNO	$116M

Top Sells

1	Bristol-Myers Squibb BMY	$355M
2	Royalty Pharma RPRX	$334M
3	McDonald's MCD	$198M
4	Union Pacific UNP	$188M
5	Hess HES	$182M

Sector Composition

1	Technology	26.31%
2	Healthcare	14.97%
3	Financials	12.6%
4	Consumer Discretionary	9.55%
5	Industrials	8.67%

#	Name	Market Value	Portfolio Weight	Shares or Principal	Shares Change %	Capital Flow
976	CNR 976 Core Natural Resources, Inc. CNR $3.98B	$0	0%	0 -45,000	Closed	–
977	TLN 977 Talen Energy Corporation Common Stock TLN $12.6B	$0	0%	0 -65,000	Closed	–
978	ATYR 978 aTyr Pharma ATYR $472M	$0	0%	0 -1,000,000	Closed	–
979	QXO 979 QXO Inc QXO $14.2B	$0	0%	0 -50,148	Closed	–
980	LINE 980 Lineage, Inc. Common Stock LINE $9.82B	$0	0%	0 -175,000	Closed	–
981	ORKA 981 Oruka Therapeutics, Inc. Common Stock ORKA $533M	$0	0%	0 -69,200	Closed	–
982	CBLL 982 CeriBell, Inc. Common Stock CBLL $583M	$0	0%	0 -318,072	Closed	–
983	INGM 983 Ingram Micro Holding Corporation INGM $4.89B	$0	0%	0 -325,000	Closed	–
984	SEPN 984 Septerna, Inc. Common Stock SEPN $523M	$0	0%	0 -300,000	Closed	–