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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HAYW icon
951
Hayward Holdings
HAYW
$3.32B
– –
-311,379
Closed -$4.71M
HNI icon
952
HNI Corp
HNI
$3.53B
– –
-720,000
Closed -$33.7M
HOUS
953
DELISTED
Anywhere Real Estate
HOUS
– –
-247,679
Closed -$2.62M
IE icon
954
Ivanhoe Electric
IE
$1.69B
– –
-258,323
Closed -$3.24M
IFRX icon
955
InflaRx
IFRX
$253M
– –
-331,113
Closed -$444K
IPG
956
DELISTED
Interpublic Group of Companies
IPG
– –
-855,288
Closed -$23.9M
IRON icon
957
Disc Medicine
IRON
$2.97B
– –
-450,000
Closed -$29.7M
K
958
DELISTED
Kellanova
K
– –
-1,053,460
Closed -$86.4M
KFY icon
959
Korn Ferry
KFY
$4.2B
– –
-575,000
Closed -$40.2M
KGC icon
960
Kinross Gold
KGC
$30.4B
– –
-250,000
Closed -$6.21M
KNSA icon
961
Kiniksa Pharmaceuticals
KNSA
$5.97B
– –
-59,000
Closed -$2.29M
KNTK icon
962
Kinetik
KNTK
$3.69B
– –
-187,500
Closed -$8.01M
LKQ icon
963
LKQ Corp
LKQ
$6.19B
– –
-234,200
Closed -$7.15M
LRMR icon
964
Larimar Therapeutics
LRMR
$436M
– –
-1,900,000
Closed -$6.14M
LYB icon
965
LyondellBasell Industries
LYB
$19.8B
– –
-54,300
Closed -$2.66M
MAS icon
966
Masco
MAS
$14.9B
– –
-293,100
Closed -$20.6M
MASI
967
DELISTED
Masimo
MASI
– –
-150,000
Closed -$22.1M
MCHP icon
968
Microchip Technology
MCHP
$40.4B
– –
-181,300
Closed -$11.6M
MGA icon
969
Magna International
MGA
$18.1B
– –
-311,576
Closed -$14.8M
MHK icon
970
Mohawk Industries
MHK
$8.97B
– –
-147,470
Closed -$19M
MLM icon
971
Martin Marietta Materials
MLM
$32.3B
– –
-27,987
Closed -$17.6M
MLTX icon
972
MoonLake Immunotherapeutics
MLTX
$1.53B
– –
-1,500,000
Closed -$10.8M
MLYS icon
973
Mineralys Therapeutics
MLYS
$2.38B
– –
-105,000
Closed -$3.98M
MRSH
974
Marsh
MRSH
$92.2B
– –
-165,061
Closed -$33.3M
MRUS
975
DELISTED
Merus
MRUS
– –
-600,000
Closed -$56.5M
37 38
39
40 41

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.