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Adage Capital Partners Portfolio holdings
AUM
$64.8B
1-Year Est. Return
42.7%
This Fund
S&P 500
This Quarter
Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
(+4.7%)
Cap. Flow
+$25.6M
Cap. Flow
% of AUM
0.04%
Top 10 Holdings %
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Merck
MRK
|
+$153M |
| 2 |
Boeing
BA
|
+$150M |
| 3 |
Dominion Energy
D
|
+$129M |
| 4 |
ConocoPhillips
COP
|
+$99.9M |
| 5 |
Revolution Medicines
RVMD
|
+$95.9M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Praxis Precision Medicines
PRAX
|
+$262M |
| 2 |
Chevron
CVX
|
+$229M |
| 3 |
Insmed
INSM
|
+$174M |
| 4 |
Procter & Gamble
PG
|
+$142M |
| 5 |
ETNB
89bio
ETNB
|
+$134M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 29.21% |
| 2 | Healthcare | 15.27% |
| 3 | Financials | 12.11% |
| 4 | Communication Services | 9.26% |
| 5 | Consumer Discretionary | 9.03% |
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Adage Capital Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.
Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.
By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.
- Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
- Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
- Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
- Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
- Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
- Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
- Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.
Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.