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Adage Capital Partners Portfolio holdings
AUM
$64.8B
1-Year Est. Return
42.7%
This Fund
S&P 500
This Quarter
Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
(+4.7%)
Cap. Flow
+$25.6M
Cap. Flow
% of AUM
0.04%
Top 10 Holdings %
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Merck
MRK
|
+$153M |
| 2 |
Boeing
BA
|
+$150M |
| 3 |
Dominion Energy
D
|
+$129M |
| 4 |
ConocoPhillips
COP
|
+$99.9M |
| 5 |
Revolution Medicines
RVMD
|
+$95.9M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Praxis Precision Medicines
PRAX
|
+$262M |
| 2 |
Chevron
CVX
|
+$229M |
| 3 |
Insmed
INSM
|
+$174M |
| 4 |
Procter & Gamble
PG
|
+$142M |
| 5 |
ETNB
89bio
ETNB
|
+$134M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 29.21% |
| 2 | Healthcare | 15.27% |
| 3 | Financials | 12.11% |
| 4 | Communication Services | 9.26% |
| 5 | Consumer Discretionary | 9.03% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
MOFG
851
DELISTED
MidWestOne Financial Group
MOFG
| $1.04M | ﹤0.01% |
27,110
-141,534
| -84% | -$5.16M |
|
852
Tenax Therapeutics
TENX
$497M
| $1.02M | ﹤0.01% |
83,333
| – | – |
|
853
Insulet
PODD
$9.6B
| $995K | ﹤0.01% |
3,500
-10,600
| -75% | -$3.31M |
|
854
Traws Pharma
TRAW
$8.26M
| $825K | ﹤0.01% |
730,000
+400,000
| +121% | +$890K |
|
|
SHMD
855
SCHMID Group
SHMD
$292M
| $774K | ﹤0.01% |
125,000
| – | – |
|
856
American Airlines Group
AAL
$10.7B
| $767K | ﹤0.01% |
50,000
-580,000
| -92% | -$7.82M |
|
857
Immunic
IMUX
$192M
| $746K | ﹤0.01% |
139,860
| – | – |
|
858
PepGen
PEPG
$157M
| $651K | ﹤0.01% |
100,000
-1,350,000
| -93% | -$7.01M |
|
859
Evolent Health
EVH
$408M
| $640K | ﹤0.01% |
160,000
-28,524
| -15% | -$159K |
|
860
ProPetro Holding
PUMP
$1.36B
| $476K | ﹤0.01% |
50,000
-100,000
| -67% | -$869K |
|
|
861
Revolution Medicines Inc Warrant
RVMDW
$114M
| $470K | ﹤0.01% |
500,000
| – | – |
|
|
IMA
862
ImageneBio Inc
IMA
$61.6M
| $460K | ﹤0.01% |
66,666
| – | – |
|
|
EVOXW
863
Evolution Global Acquisition Corp Warrants
EVOXW
| $416K | ﹤0.01% |
+945,000
| New | +$359K |
|
864
Oscar Health
OSCR
$8.04B
| $359K | ﹤0.01% |
25,000
-478,245
| -95% | -$8.27M |
|
865
Palladyne AI
PDYN
$274M
| $355K | ﹤0.01% |
83,333
| – | – |
|
866
Select Water Solutions
WTTR
$2.57B
| $316K | ﹤0.01% |
30,000
-250,000
| -89% | -$2.69M |
|
|
APXTW
867
Apex Treasury Corp Warrants
APXTW
$5.17M
| $312K | ﹤0.01% |
+1,125,000
| New | +$342K |
|
|
BCSS.WS
868
Bain Capital GSS Investment Corp Warrants
BCSS.WS
| $303K | ﹤0.01% |
+464,590
| New | +$319K |
|
869
Lifezone Metals Ltd Warrants
LZM.WS
$29.3M
| $297K | ﹤0.01% |
722,002
-211,577
| -23% | -$97.6K |
|
|
OTGAW
870
OTG Acquisition Corp I Warrants
OTGAW
| $288K | ﹤0.01% |
+900,000
| New | +$300K |
|
|
DNMXW
871
Dynamix Corp III Warrants
DNMXW
$2.36M
| $282K | ﹤0.01% |
+787,500
| New | +$297K |
|
872
OPAL Fuels
OPAL
$70.7M
| $271K | ﹤0.01% |
115,000
| – | – |
|
|
IGACR
873
Invest Green Acquisition Corp Rights
IGACR
| $257K | ﹤0.01% |
+1,350,000
| New | +$259K |
|
|
VACI.WS
874
Viking Acquisition Corp I Warrants
VACI.WS
| $252K | ﹤0.01% |
+599,654
| New | +$251K |
|
875
Acadia Pharmaceuticals
ACAD
$4.96B
| $245K | ﹤0.01% |
9,156
-2,475,000
| -100% | -$59.1M |
|
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Adage Capital Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.
Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.
By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.
- Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
- Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
- Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
- Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
- Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
- Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
- Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.
Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.