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Adage Capital Partners Portfolio holdings
AUM
$64.8B
1-Year Est. Return
42.7%
This Fund
S&P 500
This Quarter
Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
(+4.7%)
Cap. Flow
+$25.6M
Cap. Flow
% of AUM
0.04%
Top 10 Holdings %
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Merck
MRK
|
+$153M |
| 2 |
Boeing
BA
|
+$150M |
| 3 |
Dominion Energy
D
|
+$129M |
| 4 |
ConocoPhillips
COP
|
+$99.9M |
| 5 |
Revolution Medicines
RVMD
|
+$95.9M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Praxis Precision Medicines
PRAX
|
+$262M |
| 2 |
Chevron
CVX
|
+$229M |
| 3 |
Insmed
INSM
|
+$174M |
| 4 |
Procter & Gamble
PG
|
+$142M |
| 5 |
ETNB
89bio
ETNB
|
+$134M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 29.21% |
| 2 | Healthcare | 15.27% |
| 3 | Financials | 12.11% |
| 4 | Communication Services | 9.26% |
| 5 | Consumer Discretionary | 9.03% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
|
GAP
826
The Gap Inc
GAP
$7.39B
| $2.25M | ﹤0.01% |
88,000
-15,200
| -15% | -$368K |
|
|
IRD
827
Opus Genetics
IRD
$307M
| $2.22M | ﹤0.01% |
1,104,996
+150,000
| +16% | +$305K |
|
828
Community Bank
CBU
$3.44B
| $2.19M | ﹤0.01% |
38,147
+10,643
| +39% | +$612K |
|
829
Molina Healthcare
MOH
$10B
| $2.15M | ﹤0.01% |
12,400
-17,900
| -59% | -$2.94M |
|
830
Steris
STE
$22.6B
| $2.14M | ﹤0.01% |
8,460
-81,226
| -91% | -$20.4M |
|
|
MDLN
831
Medline Inc
MDLN
$29.2B
| $2.14M | ﹤0.01% |
+51,000
| New | +$2.15M |
|
832
Independent Bank
INDB
$4B
| $2.12M | ﹤0.01% |
+28,979
| New | +$2.06M |
|
833
Copart
CPRT
$26.9B
| $2.11M | ﹤0.01% |
53,900
+21,100
| +64% | +$875K |
|
|
FLOC
834
Flowco Holdings
FLOC
$876M
| $2.06M | ﹤0.01% |
110,000
-10,000
| -8% | -$167K |
|
835
Match Group
MTCH
$8.54B
| $2.04M | ﹤0.01% |
+63,116
| New | +$2.07M |
|
836
Surrozen
SRZN
$251M
| $2M | ﹤0.01% |
88,653
| – | – |
|
837
Dick's Sporting Goods
DKS
$17.8B
| $1.98M | ﹤0.01% |
+10,000
| New | +$2.18M |
|
838
Peapack-Gladstone Financial
PGC
$815M
| $1.97M | ﹤0.01% |
+70,567
| New | +$1.92M |
|
839
Astec Industries
ASTE
$1.02B
| $1.95M | ﹤0.01% |
+45,000
| New | +$2.05M |
|
|
CCRN
840
DELISTED
Cross Country Healthcare
CCRN
| $1.87M | ﹤0.01% |
230,329
+44,999
| +24% | +$492K |
|
841
Moog Inc Class A
MOG.A
$13B
| $1.84M | ﹤0.01% |
7,553
| – | – |
|
842
Century Therapeutics
IPSC
$343M
| $1.83M | ﹤0.01% |
+1,838,700
| New | +$1.12M |
|
843
Privia Health
PRVA
$2.77B
| $1.76M | ﹤0.01% |
74,346
-378,929
| -84% | -$9.22M |
|
844
Biohaven
BHVN
$2.17B
| $1.69M | ﹤0.01% |
150,000
-1,110,033
| -88% | -$13.8M |
|
845
SI-BONE Inc
SIBN
$813M
| $1.48M | ﹤0.01% |
75,000
+52,766
| +237% | +$917K |
|
846
ReNew
RNW
$2.27B
| $1.41M | ﹤0.01% |
+250,000
| New | +$1.81M |
|
|
ADGM
847
Adagio Medical Holdings
ADGM
$16.3M
| $1.31M | ﹤0.01% |
1,258,501
+200,000
| +19% | +$237K |
|
848
ATI
ATI
$30.5B
| $1.2M | ﹤0.01% |
10,468
-4,532
| -30% | -$442K |
|
849
Packaging Corp of America
PKG
$22.5B
| $1.18M | ﹤0.01% |
5,700
+1,300
| +30% | +$264K |
|
|
OMDA
850
Omada Health Inc
OMDA
$1.16B
| $1.15M | ﹤0.01% |
+72,827
| New | +$1.48M |
|
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Adage Capital Partners's Q4 2025 Portfolio in Review
As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.
Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.
By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.
- Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
- Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
- Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
- Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
- Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
- Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
- Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.
Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.