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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
TMP icon
776
Tompkins Financial
TMP
$1.44B
$4.35M 0.01%
+60,000
New +$4.11M
PSIX
777
Power Solutions International
PSIX
$761M
$4.29M 0.01%
+75,000
New +$5.35M
RLAY icon
778
Relay Therapeutics
RLAY
$4.3B
$4.23M 0.01%
+500,000
New +$3.57M
BF.B icon
779
Brown-Forman Class B
BF.B
$13B
$4.14M 0.01%
158,932
-1,400
-0.9% -$39.4K
SIRI icon
780
SiriusXM
SIRI
$10.1B
$4.13M 0.01%
206,402
-50,000
-20% -$1.07M
TNDM icon
781
Tandem Diabetes Care
TNDM
$1.29B
$4.02M 0.01%
+182,995
New +$3.3M
BEN icon
782
Franklin Resources
BEN
$17.3B
$4M 0.01%
167,500
-73,010
-30% -$1.68M
NBP
783
NovaBridge Biosciences American Depositary Shares
NBP
$197M
$3.98M 0.01%
1,000,000
-2,338,034
-70% -$10.3M
AVY icon
784
Avery Dennison
AVY
$13.2B
$3.96M 0.01%
+21,800
New +$3.77M
AKAM icon
785
Akamai
AKAM
$17.2B
$3.92M 0.01%
44,900
+14,400
+47% +$1.18M
PZZA icon
786
Papa John's
PZZA
$811M
$3.85M 0.01%
+100,000
New +$4.42M
SSTK icon
787
Shutterstock
SSTK
$217M
$3.76M 0.01%
+197,030
New +$4.21M
PSKY
788
Paramount Skydance Corp
PSKY
$10.2B
$3.76M 0.01%
280,571
-500
-0.2% -$7.81K
CAPR icon
789
Capricor Therapeutics
CAPR
$242M
$3.75M 0.01%
+130,000
New +$1.7M
STAA icon
790
STAAR Surgical
STAA
$1.15B
$3.69M 0.01%
+159,765
New +$4.12M
ICUI icon
791
ICU Medical
ICUI
$4.16B
$3.57M 0.01%
25,000
-94,862
-79% -$12.7M
COGT icon
792
Cogent Biosciences
COGT
$7.14B
$3.55M 0.01%
100,000
-462,000
-82% -$13M
SU icon
793
Suncor Energy
SU
$72.4B
$3.55M 0.01%
+80,000
New +$3.38M
PGEN icon
794
Precigen
PGEN
$2.47B
$3.54M 0.01%
846,000
– –
NPWR icon
795
NET Power
NPWR
$133M
$3.51M 0.01%
1,540,000
-969,868
-39% -$3.03M
VMC icon
796
Vulcan Materials
VMC
$36.5B
$3.51M 0.01%
12,298
-178,000
-94% -$52.2M
FWRD icon
797
Forward Air
FWRD
$563M
$3.42M 0.01%
136,825
-23,797
-15% -$536K
VTYX
798
DELISTED
Ventyx Biosciences
VTYX
$3.39M 0.01%
+375,000
New +$2.8M
HAL icon
799
Halliburton
HAL
$27.1B
$3.35M 0.01%
118,710
-216,300
-65% -$5.71M
ATO icon
800
Atmos Energy
ATO
$28.7B
$3.34M 0.01%
19,904
-126,200
-86% -$21.8M
30 31
32
33 34

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.