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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+829.83%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CAT icon
51
Caterpillar
CAT
$382B
$220M 0.33%
384,378
+57,054
+17% +$31.7M
HUBB icon
52
Hubbell
HUBB
$25.2B
$217M 0.33%
488,897
-33,975
-6% -$14.9M
OVV icon
53
Ovintiv
OVV
$17.1B
$214M 0.32%
5,462,109
+650,000
+14% +$25.2M
AON icon
54
Aon
AON
$75.9B
$214M 0.32%
606,569
-39,500
-6% -$13.8M
ABT icon
55
Abbott
ABT
$185B
$211M 0.32%
1,681,202
-615,785
-27% -$78.4M
RTX icon
56
RTX Corp
RTX
$292B
$210M 0.32%
1,142,869
+341,834
+43% +$59.4M
WM icon
57
Waste Management
WM
$90.5B
$202M 0.31%
918,710
+365,818
+66% +$78M
BSX icon
58
Boston Scientific
BSX
$70.2B
$199M 0.3%
2,082,360
+734,944
+55% +$72.1M
FERG icon
59
Ferguson
FERG
$48.5B
$198M 0.3%
889,472
+177,381
+25% +$42.4M
LIN icon
60
Linde
LIN
$221B
$198M 0.3%
463,935
+73,500
+19% +$31.5M
ISRG icon
61
Intuitive Surgical
ISRG
$133B
$193M 0.29%
340,505
+29,522
+9% +$15.7M
GS icon
62
Goldman Sachs
GS
$303B
$192M 0.29%
217,889
-25,420
-10% -$20.7M
RNAM
63
DELISTED
Avidity Biosciences
RNAM
$190M 0.29%
2,630,966
+1,430,966
+119% +$92.4M
JCI icon
64
Johnson Controls International
JCI
$88.7B
$186M 0.28%
1,555,271
-997,371
-39% -$115M
RVMD icon
65
Revolution Medicines
RVMD
$38.8B
$176M 0.27%
2,205,555
+1,463,155
+197% +$95.9M
SCHW
66
Charles Schwab
SCHW
$184B
$171M 0.26%
1,709,639
+46,000
+3% +$4.36M
EW icon
67
Edwards Lifesciences
EW
$51.1B
$167M 0.25%
1,954,631
+595,165
+44% +$48.8M
WVE icon
68
Wave Life Sciences
WVE
$1.13B
$166M 0.25%
9,786,061
-4,781,723
-33% -$48.6M
MCD icon
69
McDonald's
MCD
$188B
$166M 0.25%
541,602
-74,800
-12% -$22.9M
DHR icon
70
Danaher
DHR
$139B
$165M 0.25%
722,084
+166,580
+30% +$36.6M
AMAT icon
71
Applied Materials
AMAT
$411B
$165M 0.25%
641,726
-28,000
-4% -$6.71M
APP icon
72
Applovin
APP
$136B
$165M 0.25%
244,400
-1,800
-0.7% -$1.13M
VZ icon
73
Verizon
VZ
$197B
$164M 0.25%
4,035,772
+304,400
+8% +$12.3M
MS icon
74
Morgan Stanley
MS
$332B
$164M 0.25%
922,634
-41,600
-4% -$6.94M
C icon
75
Citigroup
C
$224B
$163M 0.25%
1,399,186
-144,800
-9% -$15M
1 2
3
4 5

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.