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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AS icon
676
Amer Sports
AS
$21B
$9.34M 0.01%
+250,000
New +$8.58M
RAPT
677
DELISTED
RAPT Therapeutics
RAPT
$9.31M 0.01%
+275,000
New +$8.54M
RRX icon
678
Regal Rexnord
RRX
$11.9B
$9.31M 0.01%
+66,326
New +$9.44M
FDMT icon
679
4D Molecular Therapeutics
FDMT
$552M
$9.26M 0.01%
1,235,156
+1,060,156
+606% +$10.8M
AES icon
680
AES
AES
$10.5B
$9.22M 0.01%
642,912
-5,300
-0.8% -$74.7K
IOT icon
681
Samsara
IOT
$22.3B
$9.22M 0.01%
260,000
+150,000
+136% +$5.81M
NP
682
Neptune Insurance Holdings
NP
$4.51B
$9.18M 0.01%
+314,981
New +$8.29M
NCLH icon
683
Norwegian Cruise Line
NCLH
$8.89B
$9.17M 0.01%
411,000
-400
-0.1% -$8.45K
WYNN icon
684
Wynn Resorts
WYNN
$10.5B
$9.17M 0.01%
76,200
-700
-0.9% -$86.6K
LZM icon
685
Lifezone Metals
LZM
$354M
$9.17M 0.01%
2,147,238
+1,472,384
+218% +$6.65M
HLT icon
686
Hilton Worldwide
HLT
$72.5B
$9.13M 0.01%
31,800
-87,100
-73% -$23.7M
DOC icon
687
Healthpeak Properties
DOC
$14.5B
$9.12M 0.01%
567,443
-65,200
-10% -$1.15M
FBRX icon
688
Forte Biosciences
FBRX
$1.57B
$9.09M 0.01%
333,333
– –
IVVD icon
689
Invivyd
IVVD
$194M
$9.04M 0.01%
+3,661,480
New +$7.62M
ALM
690
Almonty Industries
ALM
$3.81B
$9.03M 0.01%
+1,025,000
New +$7.54M
CPT icon
691
Camden Property Trust
CPT
$11B
$8.93M 0.01%
81,100
-121,514
-60% -$12.6M
LFST icon
692
Lifestance Health
LFST
$4.07B
$8.92M 0.01%
1,266,985
+816,985
+182% +$4.93M
BAX icon
693
Baxter International
BAX
$14B
$8.87M 0.01%
464,047
+146,500
+46% +$2.93M
MTD icon
694
Mettler-Toledo International
MTD
$28.5B
$8.72M 0.01%
6,258
-4,999
-44% -$6.98M
ACI icon
695
Albertsons Companies
ACI
$5.86B
$8.61M 0.01%
501,637
-50,000
-9% -$892K
CTLP
696
DELISTED
Cantaloupe
CTLP
$8.56M 0.01%
805,959
+100,000
+14% +$1.06M
TUSK icon
697
Mammoth Energy Services
TUSK
$142M
$8.46M 0.01%
4,575,000
– –
VLTO icon
698
Veralto
VLTO
$23.9B
$8.4M 0.01%
84,167
-76,700
-48% -$7.76M
GEN icon
699
Gen Digital
GEN
$16.8B
$8.34M 0.01%
306,617
-3,600
-1% -$96.9K
CINF icon
700
Cincinnati Financial
CINF
$27.5B
$8.31M 0.01%
50,900
-91,500
-64% -$14.8M
26 27
28
29 30

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.