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Adage Capital Partners

Adage Capital Partners Portfolio holdings

AUM $64.8B
1-Year Est. Return 42.7%
This Fund
S&P 500
This Quarter Est. Return
+9.6%
1 Year Est. Return
+42.7%
3 Year Est. Return
+139.29%
5 Year Est. Return
+204.38%
10 Year Est. Return
+879.75%
AUM
$66.1B
AUM Growth
+$2.94B
Cap. Flow
+$25.6M
Cap. Flow %
0.04%
Top 10 Hldgs %
31.48%
Holding
1,052
New
179
Increased
308
Reduced
377
Closed
147

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$153M
2
BA icon
Boeing
BA
+$150M
3
D icon
Dominion Energy
D
+$129M
4
COP icon
ConocoPhillips
COP
+$99.9M
5
RVMD icon
Revolution Medicines
RVMD
+$95.9M

Top Sells

Rank Stock Value
1
PRAX icon
Praxis Precision Medicines
PRAX
+$262M
2
CVX icon
Chevron
CVX
+$229M
3
INSM icon
Insmed
INSM
+$174M
4
PG icon
Procter & Gamble
PG
+$142M
5
ETNB
89bio
ETNB
+$134M

Sector Composition

Rank Sector Weight
1 Technology 29.21%
2 Healthcare 15.27%
3 Financials 12.11%
4 Communication Services 9.26%
5 Consumer Discretionary 9.03%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DLTR icon
651
Dollar Tree
DLTR
$24.9B
$10.6M 0.02%
+86,238
New +$9.24M
PALI icon
652
Palisade Bio
PALI
$363M
$10.6M 0.02%
+4,500,000
New +$8.65M
CDW icon
653
CDW
CDW
$18.1B
$10.6M 0.02%
77,500
-16,800
-18% -$2.48M
OKE icon
654
Oneok
OKE
$55.4B
$10.5M 0.02%
143,100
-365,200
-72% -$25.9M
DHI icon
655
D.R. Horton
DHI
$40.8B
$10.4M 0.02%
72,275
-180,100
-71% -$27.4M
KIM icon
656
Kimco Realty
KIM
$16.4B
$10.4M 0.02%
+511,363
New +$10.6M
CNC icon
657
CALL
Centene
CNC
$31.7B
$10.3M 0.02%
+250,000
New +$9.36M
GDDY icon
658
GoDaddy
GDDY
$11.4B
$10.2M 0.02%
82,000
-44,000
-35% -$5.69M
NSSC icon
659
Napco Security Technologies
NSSC
$1.46B
$10.2M 0.02%
243,510
+23,510
+11% +$989K
VIA
660
Via Transportation Inc
VIA
$1.75B
$10.2M 0.02%
350,000
+200,000
+133% +$8.26M
ACRS icon
661
Aclaris Therapeutics
ACRS
$851M
$10.1M 0.02%
3,371,000
-1,907,144
-36% -$4.82M
GL icon
662
Globe Life
GL
$14.4B
$10.1M 0.02%
71,900
+33,200
+86% +$4.5M
BDCI
663
BTC Development Corp
BDCI
$351M
$10M 0.02%
+1,000,000
New +$10.1M
MBVI
664
M3-Brigade Acquisition VI Corp
MBVI
$10M 0.02%
+1,000,000
New +$10.1M
AVTX icon
665
Avalo Therapeutics
AVTX
$989M
$9.99M 0.02%
550,000
+291,231
+113% +$4.92M
SLVM icon
666
Sylvamo
SLVM
$1.5B
$9.63M 0.01%
+200,000
New +$9.1M
BHF icon
667
Brighthouse Financial
BHF
$3.57B
$9.6M 0.01%
+148,100
New +$8.7M
FUL icon
668
H.B. Fuller
FUL
$3.18B
$9.51M 0.01%
160,000
– –
IVZ icon
669
Invesco
IVZ
$14B
$9.51M 0.01%
361,869
+54,844
+18% +$1.34M
DECK icon
670
Deckers Outdoor
DECK
$13.3B
$9.5M 0.01%
91,600
-3,400
-4% -$319K
HST icon
671
Host Hotels & Resorts
HST
$16B
$9.48M 0.01%
534,433
-47,700
-8% -$823K
LW icon
672
Lamb Weston
LW
$7.16B
$9.46M 0.01%
225,800
+98,900
+78% +$5.82M
ZS icon
673
Zscaler
ZS
$26.3B
$9.45M 0.01%
42,000
+8,000
+24% +$2.26M
SJM icon
674
J.M. Smucker
SJM
$12.7B
$9.42M 0.01%
96,327
-800
-0.8% -$82.7K
VEL icon
675
Velocity Financial
VEL
$715M
$9.34M 0.01%
450,046
– –
25 26
27
28 29

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Adage Capital Partners's Q4 2025 Portfolio in Review

As of Q4 2025, Adage Capital Partners held 1,052 positions worth $66.1B, up 4.7% from $63.1B the previous quarter. Its ten largest holdings account for 31% of the portfolio.

Adage Capital Partners's Q4 2025 filing shows 179 new, 308 increased, 377 reduced and 147 closed positions. Its largest new stake was Dominion Energy: 2,141,911 shares worth $125M. The largest sale was Praxis Precision Medicines, an estimated $262M.

By sector, the portfolio is most concentrated in Technology at 29% of assets, down from 30% a quarter earlier, followed by Healthcare and Financials.

  • Adage Capital Partners's largest Q4 2025 buy was Dominion Energy: 2,141,911 shares worth $125M.
  • Adage Capital Partners added most to Merck in Q4 2025, an estimated $153M increase.
  • Adage Capital Partners's biggest Q4 2025 reduction was Praxis Precision Medicines, cutting an estimated $262M.
  • Adage Capital Partners fully exited 89bio in Q4 2025, selling an estimated $134M.
  • Adage Capital Partners's ten largest holdings make up 31% of its $66.1B portfolio in Q4 2025.
  • Adage Capital Partners opened 179 new positions and closed 147 in Q4 2025.
  • Adage Capital Partners's portfolio value rose 4.7% quarter-over-quarter to $66.1B.

Based on Adage Capital Partners's 13F filing for Q4 2025, filed 17 Feb 2026.